The article is devoted to the review of the most promising MRI techniques in the diagnosis of multiple sclerosis as part of personalized medicine. A brief description of the current state of the problem is provided. Examples of promising MR research techniques are considered. The issues of clinical importance and expediency of using these techniques are discussed. The existing approaches in the diagnosis of multiple sclerosis are summarized. In conclusion, the prospects and importance of the considered methods in the structure of healthcare are summarized.