Possibilities of application of genetic and serum oncomarkers in early diagnostics of breast cancer

Abstract

Currently, mammography is the main screening method for diagnosing breast cancer (BC); but the process of carcinogenesis begins long before the appearance of a visualized tumor. For successful early diagnosis of breast cancer, a systematic approach is required, that includes all stages of tumor development. On the example of BC we consider the possibilities of integrating the recent scientific achievements of oncogenetics and proteomics with standard methods. In this article we investigate the possibilities of using genetic research, serum cancer markers and radiation methods for early diagnosis of BC. This article also presents potential options for managing high-risk development of this disease.

Radiation-Induced Damage to the Cardiovascular System After Radiation Therapy in Women With Breast Cancer

“…F or many years and today, breast cancer (BC) has been one of the most common and social ly significant women's oncological disorders in the world [1][2][3][4]. The introduction and improvement of modern instrumental diagnostic methods in practi cal medicine allow identifying this pathology at a relatively early stage of the disease.…”

“…Most research in this area is single center and often retrospective. It is difficult to unify patient groups based on cardiovascular risk factors (FR) and the volume of cardiogenic examination, concomitant cardiotoxic, chemo and targeted В продовж багатьох років і в теперішній час рак молочної залози (РМЗ) є одним з найбільших розповсюджених і соціально значущих онкологічних захворювань у жінок в світі [1][2][3][4]. Впровадження та вдосконалення сучасних інструментальних методів діагностики в практичну медицину дозволяє вияви ти дану патологію на відносно ранніх стадіях захво рювання.…”