Possibilities of Application of Combined Biologic Grafts in Acute Spinal Cord Injury (Experimental Study)

Abstract

In order to study the potentiality of spinal cord reconstruction the experimental work (65 rats) on the selection of the combined biologic graft for stimulation of optimum vascularization, elimination of nerve tissue deficit, restoration of neurologic function and survival rate of animals after dosed contusion of spinal cord was performed. In experimental group (41 rats) suspension of cultured neural stem cells was administered. Control group included 24 animals. For stimulation of compensative restorative processes in the injured spinal cord of adult rats combined grafts with use of either vascularized omentum by Goldsmith or alloaorta (adventitia turned to the spinal cord) with simultaneous of neural stem cells are the most appropriate.