Positron Emission Tomography Studies of Cerebral Blood Flow and Glucose Metabolism

Duncan, John S.

doi:10.1111/j.1528-1157.1997.tb00092.x

Cited by 7 publications

(3 citation statements)

References 70 publications

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“…Sin embargo la sensibilidad del método no es muy alta, variando según las series entre 40 a 80%. [13][14][15][16] Con los estudios de metabolismo cerebral mediante tomografía de emisión de positrones (PET) mediante la inyección de glucosa marcada, pueden demostrarse áreas de hipometabolismo coincidentes con esclerosis mesial temporal a la MRI en un 60 a 90% de los casos. [17][18][19][20] 3.…”

Section: Neuroimágenes Funcionalesunclassified

Epilepsy surgery. General concepts

Yánez Lermanda

2007

NeuroTarget

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Se revisa los conceptos generales acerca de la cirugía de la epilepsia y se describe los objetivos básicos de la selección de pacientes: 1) Definir si una epilepsia es médicamente intratable, 2) identificar la zona epileptógena y 3) determinar su relación con las áreas funcionales del cerebro. Es relevante, además, tener claro el grado de impacto que una cirugía exitosa pueda tener en el desempeño vital del paciente. Se menciona las distintas modalidades actuales del manejo quirúrgico de la epilepsia, identificando sus fortalezas y debilidades y los logros que se espera por cada patología.

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Section: Neuroimágenes Funcionalesunclassified

Epilepsy surgery. General concepts

Yánez Lermanda

2007

NeuroTarget

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“…Es ist bekannt, dass es interiktal in epileptogenen Hirnarealen zu einem Hypometabolismus von Glukose kommt. In der klinischen Diagnostik dient dessen Nachweis mittels 18 F-Deoxyglukose-Positronenemissionstomographie als sensitive Methode zur Lokalisationsdiagnostik von epileptogenen Hirnarealen (5,6,8). Der Hypometabolismus von Glukose beruht wahrscheinlich auf mehreren Mechanismen.…”

Section: Wirkmechanismen Der Ketogenen Diätunclassified

Die Ketogene Diät, Renaissance einer vergessenen Therapie: Grundlagen, Indikationen und Effektivität

Baumeister¹,

Liebhaber²,

Riemann³

et al. 2003

Kinder- und Jugendmedizin

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ZsuammenfassungDie Ketogene Diät ist eine therapeutische Ernährungsform, die durch ihren hohen Fettanteil sowie durch die Reduktion von Kohlenhydraten zur Ketonämie führt. Die Arbeit gibt einen Überblick über die für das Verständnis der Ketogenen Diät wichtigen physiologischen und biochemischen Grundlagen. Darauf aufbauend folgt die Darstellung der Indikationen sowie der Effektivität der Ketogenen Diät bei verschiedenen Erkrankungen.

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“…FDG-PET allows precise study of functional brain disorders, as these are ref lected in alterations of glucose consumption in the corresponding areas. In epileptic patients the interictal FDG-PET shows regions of hypometabolism that correspond to the areas of onset of epileptic seizures (epileptic foci) in 60% to 90% of patients with epilepsy of the temporal lobe (Duncan, 1997).…”

Section: Introductionmentioning

confidence: 99%

Cerebral Metabolism and Personality in Patients with Epilepsy of the Temporal Lobe

et al. 2006

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Extratension and introversion are stable personality styles in adult subjects. Mental functioning of the former is especially influenced by the emotions and of the latter by ideation. The aim of the present work is to analyze, using positron emission tomography with [18F]fluorodeoxyglucose (18FDG-PET), possible differences in cerebral metabolism in patients with intractable temporal lobe epilepsy (TLE) in relation to different personality styles assessed with the Rorschach test. Twenty-eight drug-resistant TLE patients with complex partial seizures were assessed by means of FDG-PET and the Rorschach test. According to location of the epileptogenic area in the dominant hemisphere and the personality style of the subject, a table of contingencies was drawn up (χ² and contingency coefficient). Finally, an analysis was made of the personality changes in patients that had received neurosurgical treatment. The results show a clear differentiation with FDG-PET as regards location of the temporal lobe affected. In 80% of subjects personality style coincided with a cerebral metabolic pattern: introversives had predominant hypometabolism in the left hemisphere and extratensives in the right. The tendency toward introversion or extratension in ambitents showed this metabolic pattern only in 38% of subjects, with 54% presenting the opposite pattern. The Rorschach test was carried out for a second time after surgical temporal resection (n = 13), and it was observed that some patients maintained their personality style while others modified it. These results suggest the existence of different hemispheric metabolic patterns in the personality styles assessed by the Rorschach test in TLE patients.

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Positron Emission Tomography Studies of Cerebral Blood Flow and Glucose Metabolism

Cited by 7 publications

References 70 publications

Epilepsy surgery. General concepts

Epilepsy surgery. General concepts

Die Ketogene Diät, Renaissance einer vergessenen Therapie: Grundlagen, Indikationen und Effektivität

Cerebral Metabolism and Personality in Patients with Epilepsy of the Temporal Lobe

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