In this paper, we consider the fixed point for a class of nonlinear sum-type operators 'A + B + C' on an ordered Banach space, where A, B are two mixed monotone operators, C is an increasing operator. Without assuming the existence of upper-lower solutions or compactness or continuity conditions, we prove the unique existence of a positive fixed point and also construct two iterative schemes to approximate it. As applications, we research a nonlinear fractional differential equation with multi-point fractional boundary conditions. By using the obtained fixed point theorems of sum-type operator, we get the sufficient conditions which guarantee the existence and uniqueness of positive solutions. At last, a specific example is provided to illustrate our result. MSC: 47H10; 47H07; 34B10; 34B18