Positive selection in the leucine-rich repeat domain of Gro1 genes in Solanum species

Ruggieri, Valentino; Nunziata, Angelina; Barone, Amalia

doi:10.1007/s12041-014-0458-9

Cited by 8 publications

(5 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The full-length DM10 Col-0 and the truncated DM10 TueScha-9 proteins differ only at 3% of shared sites, which is low for within-species variation among NLR alleles . As is typical for NLRs (Mondragón-Palomino et al 2002;Ruggieri et al 2014), Ka/Ks values above 1 were found in the LRR domain when comparing DM10 Col-0 and DM10 TueScha-9 ( Fig 5C). In contrast, DM10 Col-0 and DM10 Lerik1-3 , which are both full-length DM10 proteins but from different clades, are more differentiated in TIR and NB-ARC domains, although Ka/Ks values above 1 are also restricted to the LRR domain (Fig S5D).…”

Section: Prevalence and Genetic Differentiation Of The Dm10 Risk Allesupporting

confidence: 70%

A singleton NLR of recent origin causes hybrid necrosis inArabidopsis thaliana

Barragan

Collenberg

Wang

et al. 2020

Preprint

View full text Add to dashboard Cite

Hybrid necrosis in plants arises from conflict between divergent alleles of immunity genes contributed by different parents, resulting in autoimmunity. We investigate a severe hybrid necrosis case in Arabidopsis thaliana, where the hybrid does not develop past the cotyledon stage and dies three weeks after sowing. Massive transcriptional changes take place in the hybrid, including the upregulation of most NLR disease resistance genes. This is due to an incompatible interaction between the singleton TIR-NLR gene DANGEROUS MIX 10 (DM10), which was recently relocated from a larger NLR cluster, and an unlinked locus, DANGEROUS MIX 11 (DM11). There are multiple DM10 allelic variants in the global A. thaliana population, several of which have premature stop codons. One of these, which has a truncated LRR domain, corresponds to the DM10 risk allele. The DM10 locus and the adjacent genomic region in the risk allele carriers are highly differentiated from those in the non-risk carriers in the global A. thaliana population, suggesting that this allele became geographically widespread only relatively recently. The DM11 risk allele is much rarer and found only in two accessions from southwestern Spain -a region from which the DM10 risk haplotype is absent -indicating that the ranges of DM10 and DM11 risk alleles may be non-overlapping.

show abstract

Section: Prevalence and Genetic Differentiation Of The Dm10 Risk Allesupporting

confidence: 70%

A singleton NLR of recent origin causes hybrid necrosis inArabidopsis thaliana

Barragan

Collenberg

Wang

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…For instance, at least five R genes against diverse pathogens have been mapped to the GP21 – GP179 interval on chromosome 5 in different genetic backgrounds; Gpa and Grp1 conferring resistance to potato cyst nematodes ( Kreike et al, 1994 ; van der Voort et al, 1998 ), Nb and Rx2 conferring resistance to potato virus X ( Ritter et al, 1991 ; DeJong et al, 1997 ), and R1 conferring resistance to P. infestans ( Leonards-Schippers et al, 1992 ). In the current study, we found that Rpi2 was located in a major cluster on the long arm of chromosome 7 in which several R genes have been mapped, including Rpi1 conferring resistance to P. infestans, Gro1-4 conferring resistance to Globodera rostochiensis , and I-3 conferring resistance to Fusarium oxysporum ( Bournival et al, 1989 ; Ballvora et al, 1995 ; Kuhl et al, 2001 ; Paal et al, 2004 ; Ruggieri et al, 2014 ; Catanzariti et al, 2015 ). Clearly, this region is another hotspot for resistance genes, and can be expected to contain more resistance genes.…”

Section: Discussionmentioning

confidence: 74%

A New Resistance Gene against Potato Late Blight Originating from Solanum pinnatisectum Located on Potato Chromosome 7

Yang

Wang

et al. 2017

Front. Plant Sci.

View full text Add to dashboard Cite

Late blight, caused by the pathogen Phytophthora infestans, is one of the most devastating diseases of potato. Here, we describe a new single dominant resistance gene, Rpi2, from the Mexican diploid wild species Solanum pinnatisectum that confers high level and broad spectrum resistance to late blight. The Rpi2 locus confers full resistance to complex isolates of P. infestans, for which race specificity has not yet been demonstrated. This new gene, flanked by the RFLP-derived marker SpT1756 and AFLP-derived marker SpAFLP2 with a minimal genetic distance of 0.8 cM, was mapped to potato chromosome 7. Using the genomic sequence data of potato, we estimated that the physical distance of the nearest marker to the resistance gene was about 27 kb. The map location and other evidence indicated that this resistance locus was different from the previously reported resistance locus Rpi1 on the same chromosome from S. pinnatisectum. The presence of other reported resistance genes in the target region, such as Gro1-4, I-3, and three NBS-LLR like genes, on a homologous tomato genome segment indicates the Rpi2-related region is a hotspot for resistance genes. Comparative sequence analysis showed that the order of nine markers mapped to the Rpi2 genetic map was highly conserved on tomato chromosome 7; however, some rearrangements were observed in the potato genome sequence. Additional markers and potential resistance genes will promote accurate location of the site of Rpi2 and help breeders to introduce this resistance gene into different cultivars by marker-aided selection.

show abstract

“…The broad-spectrum resistance QTL qBWR-7 was detected in a span between 12.2 and 27.2 cM or between 10.9 and 39.2 Mb near the centromere, where recombination is less likely to occur, and comprised 23 SNP loci at the peak position (25.3 cM) (Table 1). The long arm of chromosome 7 in potato plants harbors a resistance gene hotspot containing Rpi1 and Rpi2 against Phytophthora infestans and Gro1-4 against Globodera rostochiensis (Ballvora et al 1995;Kuhl et al 2001;Paal et al 2004;Ruggieri et al 2014;Yan et al 2017); however, qBWR-7 is considered to be excluded in this hot spot. Since the effect of resistance of qBWR-7 is slightly higher than that of qBWR-3, additional ne mapping is desired to determine the accurate location and to develop molecular markers.…”

Section: Resistance Speci City To Strains and Temperaturesmentioning

confidence: 99%

Identification and characterization of resistance quantitative trait loci against bacterial wilt caused by the Ralstonia solanacearum species complex in potato

Habe¹,

Miyatake

2022

Mol Breeding

View full text Add to dashboard Cite

Bacterial wilt (BW) caused by the Ralstonia solanacearum species complex (RSSC) represents one of the most serious diseases affecting potato cultivation. The development of BW-resistant cultivars represents the most e cient strategy to control this disease. The resistance-related quantitative trail loci (QTLs) in plants against different RSSC strains have not been studied extensively. Therefore, we performed QTL analysis for evaluating BW resistance using a diploid population derived from Solanum phureja, Solanum chacoense, and Solanum tuberosum. Plants cultivated in vitro were inoculated with different strains (phylotype I/biovar 3, phylotype I/biovar 4, and phylotype IV/biovar 2A) and incubated at 24°C or 28°C under controlled conditions. Interval mapping was performed for the disease indexes using the resistant parent-derived map consisting of 1,476 single-nucleotide polymorphism (SNP) markers and the susceptible parent-derived map consisting of 2,663 SNP markers. We identi ed ve major and ve minor resistance QTLs on potato chromosomes 1, 3, 5, 6, 7, 10, and 11. The major QTLs qBWR-3 and qBWR-7 conferred stable resistance against Ralstonia pseudosolanacearum (phylotype I) and Ralstonia syzygii (phylotype IV), while qBWR-6b was a strain-speci c major resistance QTL against phylotype I/biovar 3 and was more effective at a relatively lower temperature. Therefore, we suggest that broad-spectrum QTLs and strain-speci c QTLs can be combined to develop the most effective BW-resistant cultivars for particular areas.

show abstract

Positive selection in the leucine-rich repeat domain of Gro1 genes in Solanum species

Cited by 8 publications

References 54 publications

A singleton NLR of recent origin causes hybrid necrosis inArabidopsis thaliana

A singleton NLR of recent origin causes hybrid necrosis inArabidopsis thaliana

A New Resistance Gene against Potato Late Blight Originating from Solanum pinnatisectum Located on Potato Chromosome 7

Identification and characterization of resistance quantitative trait loci against bacterial wilt caused by the Ralstonia solanacearum species complex in potato

Contact Info

Product

Resources

About