Positive reactions to common allergens in 42 atopic dogs in Japan

Masuda, Kenichi; Sakaguchi, Masahiro; Fujiwara, Shunsuke; Kurata, Kunio; Yamashita, Kohei; Odagiri, Taihei; Nakao, Yuko; Matsuki, Naoaki; Ono, Kenichiro; Watari, Toshihiro; Hasegawa, Atsuhiko; Tsujimoto, Hajime

doi:10.1016/s0165-2427(99)00166-x

Cited by 65 publications

(68 citation statements)

References 18 publications

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“…The clinical signs and their occurrence observed in this study are in accordance with other data described in the literature (Vollset, 1985;DeBoer, 1989;Sture et al, 1995;Masuda et al, 2000;Mueller et al, 2000;Zur et al, 2002). Several of the correlations described in the Results chapter are not compared with other data of the literature, because -to the authors' knowledgethese results have not yet been published by others.…”

Section: Discussionsupporting

confidence: 90%

“…Regarding the sequence of allergens these results are similar to those reported from Europe, the USA and Japan (Vollset, 1985;DeBoer, 1989;Sture et al, 1995;Masuda et al, 2000;Mueller et al, 2000), where one of the house dust mites and/or human dander are the most common. However, the proportion (%) of positive reactions to human dander was lower and that to house dust mites was higher in our study than the results reported in most veterinary surveys (Vollset, 1985;DeBoer, 1989;Sture et al, 1995;Masuda et al, 2000;Mueller et al, 2000;Zur et al, 2002).…”

Section: Discussionsupporting

confidence: 87%

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Prevalence and features of canine atopic dermatitis in Hungary

Tarpataki

Pápa

Reiczigel

et al. 2006

Acta Veterinaria Hungarica

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Medical records of 600 dogs diagnosed with atopic dermatitis were reviewed and evaluated with reference to history, geographical distribution, breed predilection, clinical signs and positive reactions to allergens as determined by intradermal skin testing (IDT) manufactured by Artuvetrin Laboratories ** . In 66.6% of dogs, the age of onset of atopic dermatitis was between 4 months and 3 years. Dogs living in the garden suburb of Budapest were more sensitive to house dust mites, fleas and moulds, and dogs from the western part of Hungary were more sensitive to weeds than to other allergens (p < 0.01). Positive reactions were most common to Dermatophagoides farinae followed by human dander. The breed distribution found in the present study was consistent with that reported in the literature, except for the breeds Hungarian Vizsla, Pumi, French bulldog, Doberman Pinscher and Bobtail which were over-represented among atopic dogs compared to the breed distribution of the general dog population of a large city in Hungary. Breeds with verified adverse reaction to food were Cocker spaniels, French bulldogs, Bullmastiffs, Bull terriers, St. Bernards, Tervurens, West Highland White terriers and American Staffordshire terriers (p < 0.05). The clinical signs of atopic dermatitis and their occurrence are in accordance with the data described in the literature.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 87%

Prevalence and features of canine atopic dermatitis in Hungary

Tarpataki

Pápa

Reiczigel

et al. 2006

Acta Veterinaria Hungarica

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“…CJ pollinosis has also been reported in dogs in Japan [10]. Our recent epidemiological study reported that approximately 20% of atopic dogs had specific IgE to crude CJ allergen [7]. Furthermore, dogs sensitive to CJ allergen showed blastogenesis and histamine release from peripheral leukocytes specific to this pollen antigen [5].…”

mentioning

confidence: 87%

Oral Allergy Syndrome Induced by Tomato in a Dog with Japanese Cedar (Cryptomeria japonica) Pollinosis.

Fujimura¹,

Ohmori

Masuda

et al. 2002

The Journal of Veterinary Medical Science

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ABSTRACT. A dog with Japanese cedar (Cryptomeria japonica, CJ) pollinosis had oral allergy syndrome (OAS) after ingesting fresh tomato. The dog showed specific IgE to both CJ and tomato allergens. As a negative control, twenty dogs without atopic dermatitis that had no exposure to tomato and no specific IgE to CJ allergen were used. They had no specific IgE to tomato allergen. Furt hermore, IgE cross-reactivity was observed between CJ and tomato allergens in the dog. We found that OAS induced by tomato exists in the dog and there is a relationship between CJ and tomato allergens. KEY WORDS: oral allergy syndrome, pollen, tomato.J. Vet. Med. Sci. 64(11): 1069-1070, 2002 In Japan, Japanese cedar (Cryptomeria japonica, CJ) pollinosis is one of the most common human allergic diseases [3]. CJ pollinosis has also been reported in dogs in Japan [10]. Our recent epidemiological study reported that approximately 20% of atopic dogs had specific IgE to crude CJ allergen [7]. Furthermore, dogs sensitive to CJ allergen showed blastogenesis and histamine release from peripheral leukocytes specific to this pollen antigen [5]. These findings suggested that CJ allergen might be associated with the pathogenesis of atopic dermatitis in dogs.Human patients showed oral allergy syndrome (OAS) after eating fruits and vegetables [1]. In human pollinosis patients, sensitivity to fruits and vegetables as OAS was reported [8]. Furthermore, there has been reported the association between some pollinosis and OAS in regard to fruits such as apple, orange, tomato, grape [2,11]. Recently, it is suggested that there is an association between human CJ pollinosis and tomato (Lycopersicon escletum) allergy [4]. However, there has been no report on OAS in dogs. In this study, we found that a dog with CJ pollinosis showed OAS induced by tomato.A 6-years-old male mixed-breed dog showed typical lesions of chronic dermatitis including erythema, eczema, and hair-loss with severe pruritus during April to October. The dog showed severer symptoms during the season of CJ pollenation. Specific IgE to both crude CJ and tomato allergens were assayed by a fluorometric ELISA as described previously [6]. Fresh tomato was washed well with water and rinded. Next, the tomato was dissected and homogenized. After centrifugation and filtration through a 0.22-µm membrane, the tomato extract was used as an ELISA antigen. The dog had specific IgE to both CJ and tomato allergens (Fig. 1). As a negative control, 20 healthy dogs without specific IgE to CJ allergen were used. There was no history of exposure to tomato in the dogs. The 20 control dogs showed no specific IgE to tomato allergens (Fig. 1). In this study, interdermal skin test could not be performed.Since the dog with atopic dermatitis had been treated with elimination diets (Eukanuba veterinary diets dry dog food, Response TM FP/Canine, Iams Co., Dayton, U.S.A.) for the last 3 years, it is considered that the dog has not been exposed to tomato. Oral provocation test was performed to * CORRESPONDENCE TO: DR. SAKAG...

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“…As in almost all the reported surveys of CAD, house dust and house dust mites were the most common allergens in the studied populations (Saridomichelakis et al 1999;Masuda et al 2000;Mueller et al 2000;Hill and DeBoer 2001;Bensignor and Carlotti, 2002;Youn et al 2002;Zur et al 2002;Nodtvedt et al 2006;Tarpataki et al 2006;Chanthick et al 2008). This is probably a true allergic response as a good correlation between serology and IDT for the house dust mite allergens was found in a study from Japan (Masuda et al 2000). In our study the mites, Dermatophagoides farinae and D. pteronyssinus, and house dust were grouped together for statistical analysis, but each one was tested separately by IDT (house dust was tested in the earlier period of the study only).…”

Section: Allergens In Dogs With Cad and Their Associations With Signamentioning

confidence: 71%

“…CAD is difficult to diagnose because there is no specific diagnostic test or pathognomonic sign; rather, diagnosis is based on meeting certain criteria and eliminating other pruritic diseases (Willemse, 1986;Reedy et al 1997;Griffin and DeBoer, 2001;Scott et al 2001;Favrot et al 2010). Published studies have described the disease in various continents and countries (Saridomichelakis et al 1999;Masuda et al 2000;Mueller et al 2000;Youn et al 2002;Zur et al 2002;Tarpataki et al 2006;Nodtvedt et al 2007;Picco et al 2008). However, the multiple aspects and presentations of the disease in the Middle East have not been reported, and the aim of this study is to describe CAD as well as the common environmental allergens associated with affected dogs in this part of the world.…”

mentioning

confidence: 95%

Canine atopic dermatitis in the Middle East: clinical signs, signalment and common allergens

Zur¹,

Skorinsky²,

Bdolah‐Abram³

2012

Vet. Med. - Czech

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ABSTRACT:The aim of the study was to examine for the first time the various aspects of canine atopic dermatitis (CAD) presenting in a Middle Eastern country. Medical records of 164 dogs diagnosed with CAD were evaluated. Associations between signalment, lifestyle, clinical signs and allergens were evaluated statistically. Labrador Retriever, German Shepherd dog, Boxer, French Bulldog, Golden Retriever and Shar-Pei breeds were presented more frequently than the regular hospital population (P < 0.0001), and had an earlier disease onset time (P < 0.01). In 22 dogs (13%) signs of CAD were noticed at less than six months of age. Most dogs (75%) lived indoors. Most dogs (83%) had lesions on the ventral part of the body and 68% had foot lesions. After excluding flea allergy dermatitis by implementing strict flea control, 60% of the dogs presented with dorsal distribution of skin lesions. Dogs with ventral lesions were younger when clinical signs first appeared (P < 0.05). Most of the dogs were allergic to dust and/or dust mites (75.6%), with weeds and trees as the next most common allergens. CAD is similar worldwide, but geographic differences may be attributable to genetic pools and allergen loading. This study also shows that early onset of clinical signs, especially in breeds predisposed to CAD and with a dorsal distribution of skin lesions, should not rule out the diagnosis of CAD.

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Positive reactions to common allergens in 42 atopic dogs in Japan

Cited by 65 publications

References 18 publications

Prevalence and features of canine atopic dermatitis in Hungary

Prevalence and features of canine atopic dermatitis in Hungary

Oral Allergy Syndrome Induced by Tomato in a Dog with Japanese Cedar (Cryptomeria japonica) Pollinosis.

Canine atopic dermatitis in the Middle East: clinical signs, signalment and common allergens

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