Positive Protosystolic Peak of Coronary Arterial Blood Flow. A New Index of Epicardial Compliance?

Verlato, G.; Cevese, Antonio; Poltronieri, Roberto

doi:10.1007/978-94-009-4634-7_50

Cited by 1 publication

(1 citation statement)

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“…Reneman and measured pressure pulse transmission at the anterior descending branch of the left coronary artery, the volume stiffness of the epicardial arteries were derived from the pressure wavefront velocity. Verlato and Poltronieri (1994) estimated the epicardial capacitance as the area of the protosystolic peak of the coronary flow divided by the aortic pulse pressure. They found that the protosystolic peak is an useful index of epicardial compliance at basal coronary vasomotor tone.…”

Section: Coronary Input Impedance Chracterizationmentioning

confidence: 99%

Modeling of the Coronary Circulatory System

Liao¹,

Li²

2005

Cardiovasc Eng

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The dynamics of the coronary system is complicated by its dependence on the mechanical properties of the coronary vessels, the anatomical distribution of the vasculature, the biochemical and neurohormonal regulation, and the effect of myocardial contraction. Several types of coronary system models were proposed, focusing on different aspects of coronary system behavior and supported by different animal experiment methodologies. The lumped models were based on well-controlled coronary pressure-flow measurement and simplified assumptions. They are probably most useful for interpreting hemodynamic data measured in modern catheterizaton labs. Anatomical models, with the advancement in morphometric research, coronary angiography, and video densitometry, provided branching pattern, geometric distribution, and distensibility of coronary vessels. Mathematical description based on vascular waterfall theory, intramyocardial pump model, and time varying elastance concept provided some explanation of the interaction between the coronary system and myocardial contraction. More accurate models would include intramyocardial pressure, microcirculatory hemodynamics, coronary flow regulation, and myocardial oxygen supply and consumption. The combination of different models, may lead to a more comprehensive understanding of the coronary system.

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Section: Coronary Input Impedance Chracterizationmentioning

confidence: 99%