Positive Interaction of Ethanol and Kava Resin in Mice

Jamieson, Dara G.; Duffield, P.H.

doi:10.1111/j.1440-1681.1990.tb01350.x

Cited by 66 publications

(22 citation statements)

References 10 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…141 Kava may interact with benzodiazepines; there is 1 controversial case report involving alprazolam. 142 While the consumption of large amounts of alco-hol has been noted to potentiate the actions of kava in mice, 143 administration of a standardized kava extract in a placebo-controlled, doubleblind study showed few adverse effects. 144 The possibility exists that concomitant administration may potentiate the action of other centrally mediated agents.…”

Section: 137mentioning

confidence: 99%

Herbal Remedies in Psychiatric Practice

Wong¹,

Smith²,

Boon³

1998

Arch Gen Psychiatry

197

123

View full text Add to dashboard Cite

Patients' use of alternative and complementary health services has created a need for physicians to become informed about the current literature regarding these treatments. Herbal remedies may be encountered in psychiatric practice when they are used to treat psychiatric symptoms; produce changes in mood, thinking, or behavior as a side effect; or interact with psychiatric medications. English-language articles and translated abstracts or articles (where available) found on MEDLINE and sources from the alternative/complementary health field were reviewed. Each herb was assessed for its safety, side effects, drug interactions, and efficacy in treating target symptoms or diagnoses. A synopsis of the information available for each herb is presented. In many cases the quantity and quality of data were insufficient to make definitive conclusions about efficacy or safety. However, there was good evidence for the efficacy of St John's wort for the treatment of depression and for ginkgo in the treatment of memory impairment caused by dementia. More research is required for most of the herbs reviewed, but the information published to date is still of clinical interest in diagnosing, counseling, and treating patients who may be taking botanical remedies.

show abstract

Section: 137mentioning

confidence: 99%

Herbal Remedies in Psychiatric Practice

Wong¹,

Smith²,

Boon³

1998

Arch Gen Psychiatry

197

123

View full text Add to dashboard Cite

show abstract

“…Ethanol can enhance the hypnotic effect of kava-kava [96]. It can potentiate barbiturates and benzodiazepines [97].…”

Section: Potential Side Effects and Drug Interactionsmentioning

confidence: 99%

Herbal medicine: Is it an alternative or an unknown? A brief review of popular herbals used by patients in a pain and symptom management practice setting

Leak

1999

Current Review of Pain

View full text Add to dashboard Cite

This article will briefly discuss herbals frequently used by patients in a pain and symptom management practice setting with regard to common indications, potential side effects, and drug interactions, as well as a review of available research on each substance. An overview of the regulatory morass that continues to surround the herbal products industry will be presented. The author will examine possible ethic implications of providing care to patients utilizing alternative therapies. Future developments and studies in the field of herbal therapies will be considered.

show abstract

“…A synergistic effect was reported in mice using hypnotic doses of kava and alcohol (76). However, a clinical trial in 20 volunteers (77) given 100 mg of kava extract three times per day for 8 days tested the added effects of alcohol by adding ethanol on days 1, 4, and 8 (doses of alcohol were sufficient to achieve blood alcohol levels of 0.05%).…”

Section: Effects Of Dietary Supplementsmentioning

confidence: 99%

Diagnostic and Statistical Manual of Mental Disorders

2018

The SAGE Encyclopedia of Intellectual and Developmental Disorders

View full text Add to dashboard Cite

Alternative therapies are widely used by consumers. A number of herbs and dietary supplements have demonstrable effects on mood, memory, and insomnia. There is a significant amount of evidence supporting the use of Hypericum perforatum (St. John's wort) for depression and Ginkgo biloba for dementia. Results of randomized, controlled trials also support the use of kava for anxiety and valerian for insomnia. Although evidence for the use of vitamins and amino acids as sole agents for psychiatric symptoms is not strong, there is intriguing preliminary evidence for the use of folate, tryptophan, and phenylalanine as adjuncts to enhance the effectiveness of conventional antidepressants. S-adenosylmethionine seems to have antidepressant effects, and omega-3 polyunsaturated fatty acids, particularly docosahexaenoic acid, may have mood-stabilizing effects. More research should be conducted on these and other natural products for the prevention and treatment of various psychiatric disorders.

show abstract

Positive Interaction of Ethanol and Kava Resin in Mice

Cited by 66 publications

References 10 publications

Herbal Remedies in Psychiatric Practice

Herbal Remedies in Psychiatric Practice

Herbal medicine: Is it an alternative or an unknown? A brief review of popular herbals used by patients in a pain and symptom management practice setting

Diagnostic and Statistical Manual of Mental Disorders

Contact Info

Product

Resources

About