Positive Interaction Between Light Iris Color and Ultraviolet Radiation in Relation to the Risk of Uveal Melanoma

Occupational Cooking and Risk of Uveal Melanoma: a Meta-analysis

“…9 full-text publications were preliminarily included into this meta-analysis (Ajani et al, 1992;Holly et al, 1996;Guenel et al, 2001;Monarrez-Espino et al, 2002;Stang et al, 2003;Lutz et al, 2005;Schmidt-Pokrzywniak et al, 2009;Schmidt-Pokrzywniak et al, 2010;Behrens et al, 2011). After full-text review of those 9 papers, 2 studies were excluded because they contained overlapping data (Monarrez-Espino et al, 2002;Schmidt-Pokrzywniak et al, 2009), and another studies excluded because they were lack of necessary data (Ajani et al, 1992;Holly et al, 1996). Thus, five case-control studies involving a total of 1199 cases and 6927 controls were finally included into our meta-analysis (Guenel et al, 2001;Stang et al, 2003;Lutz et al, 2005;Schmidt-Pokrzywniak et al, 2010;Behrens et al, 2011).…”

The pathology of ocular cancer

“…4 Uveal melanoma's propensity for lightly pigmented patients and the posterior part of the uveal tract suggests that UV light may have a role in its pathogenesis, but several studies in this regard are inconclusive. 5,6 Although retinoblastoma is the most common eye cancer on a worldwide basis, uveal melanoma is the most common ocular cancer in Europe and the United States, exceeding retinoblastoma by a factor of 6.…”

“…29 Most larger melanomas that are enucleated are mixed cell melanomas that contain a mixture of spindle and epithelioid cells. 6 Other prognostic factors that can be assessed during routine histopathological examination include tumor location, mitotic activity, the presence or absence of extrascleral invasion, lymphocytic and melanophagic infiltration, and vascular mimicry patterns.…”

18-årsgrensen for solariebruk skal håndheves

“…A new study adds data to support this conclusion (Schmidt-Pokrzywniak et al, 2009), with the risk increased when exposure started at a younger age.…”

“…), 827 population controls (selected from list of residence, matched 2:1 on age (5-yr age groups), sex and region) and 187 sibling controls (matched 1:1 by age (+/− 10 yr) and sex when possible) (Schmidt-Pokrzywniak et al, 2009). Exposure was assessed by a self-administered postal questionnaire and computer-assisted telephone interviews.…”