Positive H‐Y antigen testing in a case of XY gonadal absence syndrome

Schulte, Michael-JÖRG

doi:10.1111/j.1399-0004.1979.tb01353.x

Cited by 6 publications

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The patients with this disease are phenotypically female, though genetically male and show absence of internal sexual ducts and various degrees of masculinization of external genitalia. The H-Y antigen which is thought to be the organizer of gonadal differentiation for the testis (Wachtel & Ohno 1979) has been examined, so far, in one case only and the result was positive (Schulte 1979). We report here another case of agonadism in which the H-Y antigen test was performed.…”

mentioning

confidence: 77%

Agonadism with positive H‐Y antigen

et al. 1984

View full text Add to dashboard Cite

A 30‐year‐old phenotypic female was investigated because of absence of the vagina. Her serum gonadotropins were elevated while testosterone was in the normal range for females. Stimulation with human chorionic gonadotropin (hCG) gave no response of testosterone. No uterus, Fallopian tubes, Wolffian derivatives, or the gonads were found at laparotomy. Chromosome analysis showed a46, XY karyotype. The expression of the H‐Y antigen was positive. The results suggest that testicular degeneration in agonadism is not caused by a defective H‐Y antigen.

show abstract

mentioning

confidence: 77%

Agonadism with positive H‐Y antigen

et al. 1984

View full text Add to dashboard Cite

show abstract

Testicular regression in a patient with virilized female phenotype

Rosenberg

Mustacchi²,

Braz³

et al. 1984

Am. J. Med. Genet.

View full text Add to dashboard Cite

The 16-year old girl studied here had ambiguous external genitalia, ie, enlarged clitoris, pseudo vagina, and rudiments of Wolffian tubes. Her karyotype was 46,XY and she was H-Y antigen-positive. In spite of absence of gonadal tissue, genital virilization suggests presence of testes during embryogenesis. This patient is compared to 20 others with testicular regression from the literature. Autosomal-recessive inheritance of this condition is proposed.

show abstract

Ovarian Dysgenesis and Related Genetic Disorders

Simpson

1987

Gynecologic Endocrinology

View full text Add to dashboard Cite

Positive H‐Y antigen testing in a case of XY gonadal absence syndrome

Abstract: H‐Y antigen testing was positive in a case of pseudohermaphroditism due to XY gonadal absence syndrome. In conclusion, H‐Y antigen may be present even in the absence of testes. Also, the syndrome could not have originated from a defect in the H‐Y antigen system.

Cited by 6 publications

References 5 publications

Agonadism with positive H‐Y antigen

Agonadism with positive H‐Y antigen

Testicular regression in a patient with virilized female phenotype

Ovarian Dysgenesis and Related Genetic Disorders

Contact Info

Product

Resources

About