“…These include NC2, TFIIA, TFIIB (77), Mbf1p (78), Spt3p, Spt8p, and Ada1p subunits of SAGA (79,80), TFIID Taf1p and TAND (58,59,81,82), Med8p and Med20p subunits of Mediator (83), Brf1p subunit of TFIIIB (84), TAF I 48 subunit of SL1 (85), N-terminal domain of Mot1p (86), SNAP190 subunit of SNAP C (87), and the NOT complex (88). Interestingly, many of these TBP-targeted factors both activate and repress transcription (76).…”