Position statement of the Interamerican Society of Cardiology (IASC) on the current guidelines for the prevention, diagnosis and treatment of arterial hypertension 2017–2020

Wyss, Fernando; Coca, António; López‐Jaramillo, Patricio; Ponte‐Negretti, Carlos I.; Restrepo, Gustavo; Lanas, Fernando; Pérez, Gonzalo; Barroso, Weimar Sebba; Noval, Reynaldo de la; Paris, Juan Verdejo; Almonte, Claudia; Valdez, Osiris; Medina, Ángel; Valoy, Laura Valdez; Barragán, Adriana Cecilia Puente; Cobos, Leonardo; Ullauri, Vladimir; Terán, Joffre Lara; Liprandi, Álvaro Sosa; Piskorz, Daniel; Barbosa, Eduardo; Jaramillo, Patrício López; Parati, Gianfranco; Íñiguez, Andrés

doi:10.1016/j.ijchy.2020.100041

Cited by 25 publications

(21 citation statements)

References 53 publications

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“…For example, the prevalence of HTN in people with diabetes was 80.4% based on ACC/AHA 2017 and 67.6% using JNC7 guidelines. This is comparable to other US studies in which prevalence rates of ~70% in those with diabetes were found using JNC7 guidelines [ 2 , 3 , 19 ]. This cohort of patients are likely to benefit substantially from early drug treatment.…”

Section: Discussionsupporting

confidence: 88%

“…Although they are written for a US population, they have global impact. Despite this, HTN remains a significant contributor to the global burden of disease, and it remains an important risk factor for cardiovascular morbidity and mortality [ [2] , [3] , [4] ]. HTN has previously been defined by the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) as individuals who have a systolic BP ≥ 140 mmHg or a diastolic BP ≥ 90 mmHg or take any prescribed drugs to control BP [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of hypertension and controlled hypertension among United States adults: Evidence from NHANES 2017-18 survey

Rana

Oldroyd

Islam

et al. 2020

International Journal of Cardiology Hypertension

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Prevalence of hypertension and controlled hypertension among United States adults: Evidence from NHANES 2017-18 survey

Rana

Oldroyd

Islam

et al. 2020

International Journal of Cardiology Hypertension

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“…For example, the prevalence of HTN in people with diabetes was 80.4% based on ACC/AHA 2017 and 67.6% using JNC7 guidelines. This is comparable to other US studies in which prevalence rates of ∼70% in those with diabetes were found using JNC7 guidelines [2,4,15]. This cohort of patients are likely to benefit substantially from early drug treatment.…”

Section: Discussionsupporting

confidence: 83%

“…Although they are written for a US population, they have global impact. Despite this, HTN remains a significant contributor to the global burden of disease, and it remains an important risk factor for cardiovascular morbidity and mortality [2–4]. HTN has previously been defined by the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) as individuals who have a systolic BP ≥140 mmHg or a diastolic BP ≥90 mmHg or take any prescribed drugs to control BP [5].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of hypertension and controlled hypertension among United States adults: Evidence from NHANES 2017-18 survey

Rana

Oldroyd

Islam

et al. 2020

Preprint

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Background: This study aims to compare the prevalence of hypertension (HTN) and controlled hypertension (CHTN) in US adults and determine the absolute difference in the prevalence of HTN and CHTN between the JNC7 and ACC/AHA 2017 guidelines. Methods: Data for this study were derived from the most recent cycle of the National Health and Nutrition Examination Survey (NHANES) 2017-2018. After excluding participants with missing systolic blood pressure (BP) or diastolic BP and aged <18 years, 4730 participants were included in the final analyses. BP was defined as the average of the first three measurements. The prevalence of HTN and CHTN, including absolute differences of these prevalences, were estimated using both JNC7 and ACC/AHA 2017 guidelines. Results: The overall weighted prevalence of HTN was 31.7% (95% CI: 28.7, 34.8) based on JNC7, while the corresponding prevalence was 45.6% (95% CI: 43.0, 48.3) when new guideline of ACC/AHA was used. Of the people who had HTN according to the JNC7 and ACC/AHA 2017 guidelines, 48.2% (95% CI: 44.4-52.0) and 21.0% (95% CI: 18.1-24.2) had a controlled blood pressure level, respectively. When blood pressure was assessed using both guidelines, the greatest absolute increase in rates of HTN and CHTN was 17.4% and 30.0% in people aged 40-59 years, respectively. Conclusion: Given the high burden of disease due to complications arising from untreated HTN, as well as the higher costs of untreated disease, new guidelines have important public health implications to early detection of patients at risk and prevent complications across different populations.

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“…According to incomplete statistics, the number of people worldwide suffered from diabetes and hypertension are approximately 425 million and 1.4 billion, respectively. [1][2][3] Both of them belong to complex metabolic diseases and share common risk factors. They are also known as the complication of each other probably due to the intertwined pathophysiological pathways, and associated with a higher risk of stroke and heart attack.…”

Section: Introductionmentioning

confidence: 99%

Identification of C-phycocyanin-derived Peptides as Angiotensin Converting Enzyme and Dipeptidyl Peptidase IV Inhibitors via Molecular Docking and Molecular Dynamic Simulation

Pan¹,

Zhou²,

Li³

et al. 2020

ES Food Agrofor.

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The objective of this study was to screen angiotensin converting enzyme (ACE) and dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from simulated gastrointestinal digestion of C-phycocyanin using in silico methods. The molecular interaction and complex stability of C-phycocyanin-derived peptides with two receptors (ACE and DPP-IV) were studied. After in silico enzyme digestion, 32 unreported peptides were screened by comparing with BIOPEP-UWM and AHTPDB database, and none of them exhibited toxicity to the body based on ADMET predicted results. Moreover, four unreported peptides (LSPSW, CAR, GEF and MAAC) were predicted to have good biological activity. Molecular docking showed that the four peptides all formed hydrogen bonds and hydrophobic interactions with the key groups in ACE and DPP-IV active pockets, of which LSPSW was strongest binding peptide and supposed to be the most potential inhibitor for ACE and DPP-IV. LSPSW-ACE and LSPSW-DPP-IV systems were found to reach equilibrium within 50 ns of MD simulation according to their RMSD and energy results. In addition, the binding of LSPSW to ACE and DPP-IV caused the structure of receptor to be more compact. This study can provide valuable information for the development of C-phycocyanin-derived peptides as ACE and DPP-IV inhibitors.

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Position statement of the Interamerican Society of Cardiology (IASC) on the current guidelines for the prevention, diagnosis and treatment of arterial hypertension 2017–2020

Cited by 25 publications

References 53 publications

Prevalence of hypertension and controlled hypertension among United States adults: Evidence from NHANES 2017-18 survey

Prevalence of hypertension and controlled hypertension among United States adults: Evidence from NHANES 2017-18 survey

Prevalence of hypertension and controlled hypertension among United States adults: Evidence from NHANES 2017-18 survey

Identification of C-phycocyanin-derived Peptides as Angiotensin Converting Enzyme and Dipeptidyl Peptidase IV Inhibitors via Molecular Docking and Molecular Dynamic Simulation

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