The subject's relevance stems from the rapid advancement of science and technology, which drives the extensive utilization of controlled mobile robot models with manipulators across diverse domains. The study aims to explore the development of versatile mobile robotic devices using manipulators for space applications, drawing from the expertise of specialists at Almaty University of Power Engineering and Telecommunications. The methodological approach is based on a combination of methods of system analysis of the principles of building a highly functional model of a mobile robot made based on manipulation devices, with an analytical study of the main directions of using mobile robots in the space sphere. The study underscores designing space mobile robots based on human body dynamics, stressing the necessity of robust mathematical models and specialized software, meeting stringent reliability, simplicity, and safety criteria. The findings underscored the critical role of manipulator-based mobile robot modeling in space technology development, offering practical insights for developers in various technological fields, including aerospace. The practical implications of the research include the possibility of developing and implementing reliable and efficient manipulative mobile robots for use in space, which will help to increase the efficiency of space operations and reduce risks to humans.