Pos1224 rheumatic Manifestations in Covid-19 Patients - Single-Center Experience Amidst the Pandemic

Bogdanova-Petrova, S.; Georgiev, Tsvetoslav; Gerganov, G.; Hristova, S. V.; Dimitrov, Stoyan; Shivacheva, T.

doi:10.1136/annrheumdis-2021-eular.2836

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is usually diffuse rather than localized. According to different sources, the incidence varies from 49.3 to 60.9% in patients with COVID-19 [46]. Myalgia during SARS-CoV 2 infection is associated with elevated levels of interleukin-6.…”

Section: Types Of Pain In Covid-19mentioning

confidence: 99%

Pain in COVID-19 and features of pathogenetic molecular mechanisms

Bogdanova¹,

Shivacheva²,

Georgiev³

et al. 2023

RBJ

View full text Add to dashboard Cite

Although it has been almost three years since the World Health Organization (WHO) declared a pandemic, COVID-19 is still an unsolved problem, thereby attracting great scientific interest. The disease has a heterogeneous clinical picture with multiple manifestations from different organs and systems. Currently, COVID-19 is perceived as a polysyndromic inflammatory disease involving not only the respiratory system, but also the musculoskeletal system, the cardiovascular system, the skin, the excretory and the nervous system, and is accompanied by a number of hematological, gastrohepatoenterological and endocrine disorders. Various pain phenomena also appear in the clinical presentation of the disease, often as a single manifestation or in combination with symptoms from different organs and systems. The pathogenesis of pain is complex and there is still no consensus on the exact driving mechanisms. Several different signaling pathways play an important role in the generation of pain impulses and perception. They are different for different types of pain. At this stage, the role of angiotensin-converting enzyme 2 (ACE), the renin-angiotensin system (RAC), angiotensin 2 receptors (AT2R), direct neuronal invasion of the virus, the involvement of pro-inflammatory cytokines, hypoxia, the involvement of macrophages, is discussed. as well as the role of overactivity of the immune system, causing the so-called "cytokine storm". Pain is the result of complex biochemical processes influenced to varying degrees by biological, physiological and social factors. Our knowledge at this stage remains scarce and is the subject of many studies on the key pathogenic mechanisms. Therefore, the purpose of this review is to describe the known mechanisms for the occurrence and persistence of pain in patients with COVID-19, as well as to classify the pain phenomena and present its most common localizations. The diagnosis and treatment of COVID-19 and associated pain should be carried out by a multidisciplinary team of specialists, given the heterogeneous clinical presentation of the disease.

show abstract

Section: Types Of Pain In Covid-19mentioning

confidence: 99%

Pain in COVID-19 and features of pathogenetic molecular mechanisms

Bogdanova¹,

Shivacheva²,

Georgiev³

et al. 2023

RBJ

View full text Add to dashboard Cite

show abstract

“…Myalgia, defined as muscle pain, has been frequently reported in COVID-19 infected patients with a prevalence range from 11 to 50% in large cohort studies 3 . Arthralgia has also been reported in 2.5% of patients 4 ; meanwhile, fatigue is the most common musculoskeletal symptom reported in 63%, followed by back pain 50.5% in patients with COVID 19 5 . As such, the musculoskeletal symptoms reported in early stage of COVID-19 infection may also be reported in patients, who needed intensive care unit 6 .…”

Section: Introductionmentioning

confidence: 99%

The Incidence of Musculoskeletal Manifestations among Patients with COVID 19 Infection

Sheelan Faroz Aref,

Aryan Mohamadfatih Jalal,

Shwan Kader Media

2022

IJPHRD

View full text Add to dashboard Cite

Background-Patients with COVID-19 may manifest musculoskeletal symptoms; myalgia is frequently detected in COVID-19 infected patients. The study aims to examine the incidence of musculoskeletal manifestations in the Iraqi Kurdistan Region and its correlation with the disease severity, and the patient's outcomes. Further, it attempts to correlate the disease severity with the smoking.Method-A sample of one thousand (1000) COVID-19 infected patients from the Iraqi Kurdistan Region, were examined in an observational cross-sectional study to obtain relevant data for the patients treated in the COVID-19 care centres in Erbil city. The study lasted from 15 August 2020 to 15 June 2021. Conclusion-The study shows that the musculoskeletal manifestations are frequent in COVID-19 infected patients; 79.4% of patients had fatigue, 66.8% had myalgia, 56.9% had backache, and 41.5% had arthralgia, fatigue is the most common symptom. The smokers manifest severe or critical conditions of the disease.

show abstract

Pos1224 rheumatic Manifestations in Covid-19 Patients - Single-Center Experience Amidst the Pandemic

Cited by 2 publications

References 0 publications

Pain in COVID-19 and features of pathogenetic molecular mechanisms

Pain in COVID-19 and features of pathogenetic molecular mechanisms

The Incidence of Musculoskeletal Manifestations among Patients with COVID 19 Infection

Contact Info

Product

Resources

About