Pos0394 validation of the Sle Susceptible Gene Loci in the Multi-Ethnic Malaysian Systemic Lupus Erythematosus (Sle) Cohort and Their Associations With Clinical Manifestation
Abstract:BackgroundSystemic Lupus erythematous (SLE) is an autoimmune disease with a wide spectrum of clinical manifestations. Asian patients including Malaysia tend to have more severe disease with renal involvement. The differences could be due to the interactions between genetic and environmental factors. Thus, identifying the genetic associations from diverse populations provides a better understanding on the genetic architecture of this heterogeneous disease.ObjectivesThe primary objective of this study was to val… Show more
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