POS-730 Cutaneous leishmaniasis in a renal transplant recipient

Abstract

Conclusions: PTMD is a severe metabolic complication. It had serious impact on cardiovascular complications that can influence graft and patient survival .Early identification and treatment of PTMD may improve outcomes .

Epidemiology, Clinical Characteristics, Diagnostic Work Up, and Treatment Options of Leishmania Infection in Kidney Transplant Recipients: A Systematic Review

“…At the end of the process, we included 66 retrospective case reports and 4 retrospective case series. According to the modified Newcastle–Ottawa Scale, 11 items were classified as low-quality [ 7 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 ], 34 as average-quality [ 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 ], and 25 as high-quality studies [ 4 , 10 , 59 , 60 , 61 …”

“…Information regarding the country of origin or travel activity was available for 153/159 (96.2%) patients. The vast majority ( n = 143) of KT recipients with Leishmaniasis came from or had travelled to endemic regions, especially South America, North Africa, the Middle East, India, or the Mediterranean basin [ 4 , 16 , 17 , 18 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 30 , 31 , 34 , 35 , 36 , 38 , 40 , 41 , 42 , 44 , 45 , 48 , 50 , 51 , 52 , 54 , 55 , 56 , 57 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 69 , 70 , 71 , 72 , 73 , 75 , 76 , 78 , 79 , 81 …”

“…Most episodes of Leishmania infection were registered in Brazil ( n = 66) [ 22 , 29 , 30 , 40 , 58 , 68 , 74 , 79 ]. Several cases were also reported in the Mediterranean basin ( n = 61), such as Spain ( n = 20) [ 18 , 27 , 36 , 41 , 48 , 53 , 55 , 61 , 63 , 68 , 78 ], Italy ( n = 14) [ 31 , 33 , 35 , 42 , 44 , 45 , 51 , 72 , 81 ], France ( n = 10) [ 25 , 39 , 64 ], Tunisia ( n = 8) [ 7 , 17 , 34 , 52 , 62 , 69 ], Greece ( n = 4) [ 54 ], Turkey ( n = 3) [ 59 , 67 , 77 ], Malta ( n = 1) [ 38 ], and Algeria ( n = 1) [ 23 ]. Overall, European countries outside the Mediterranean basin recorded a small number of infections: Portugal ( n = 2) [ 24 , 66 ], Switzerland ( n ...…”

“…The donor type was available for 112/159 (70.4%) patients: 64 received a deceased donor kidney [ 7 , 17 , 22 , 27 , 28 , 30 , 31 , 35 , 39 , 40 , 46 , 47 , 50 , 51 , 52 , 53 , 54 , 60 , 61 , 63 , 65 , 66 , 69 , 72 , 73 , 78 , 79 , 81 ] and 50 had a living donor [ 4 , 17 , 21 , 22 , 23 , 26 , 29 , 30 , 34 , 38 , 40 , 54 , 57 , 59 , 62 , 67 , 68 , 70 , 71 , 72 , 76 , 77 , 79 ].…”

“…Maintenance immunosuppression was very heterogeneous. Most patients were on a CNI-based triple-agent scheme with tacrolimus ( n = 54) [ 17 , 20 , 21 , 23 , 24 , 25 , 26 , 27 , 30 , 31 , 34 , 40 , 41 , 49 , 58 , 59 , 62 , 66 , 72 , 73 , 79 , 81 ] or cyclosporin ( n = 45) [ 4 , 17 , 29 , 30 , 33 , 35 , 36 , 39 , 40 , 45 , 46 , 47 , 50 , 51 , 53 , 54 , 60 , 61 , 63 , 64 , 65 , 69 , 70 , 71 , 74 , 75 , 78 , 79 ], AZA ( n = 51) […”