Portal vein entrance of splenic erythrocytic progenitor cells and local hypoxia of liver, two events cause intrahepatic splenosis

Kwok, Ching-Ming; Chen, Yen‐Ting; Lin, Han-Tso; Su, Cheng-Hsi; Liu, Yu-Shi; Chiu, Yi-Chon

doi:10.1016/j.mehy.2006.04.064

Cited by 54 publications

(43 citation statements)

References 16 publications

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“…Thoracic splenosis cases have also been reported in patients with accompanying diaphragm rupture (8). Splenic implants have an advanced transplantation ability along with lack of tissue selectivity, thus, splenosis cases that mimic intrabronchial, pericardial, subcutaneous, or even stomach, kidney and liver tumors have been reported (9,10). The size of intrahepatic splenosis may vary from a few millimeters up to 12 centimeters (11).…”

Section: Discussionmentioning

confidence: 99%

Intrahepatic splenosis after splenectomy performed for idiopathic thrombocytopenic purpura

Toktaş

Yavuz

İliklerden

et al. 2015

UCD

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The term splenosis describes autotransplantation or implantation of ectopic splenic tissue within the abdominal cavity or in any other unusual body compartment. In addition to the diagnostic dilemma it causes, splenosis may also lead to persistence or recurrence of hematologic dysfunctions by its preserved immune activity especially in cases of splenectomy due to hematologic indications. Herein, we present a 40-year-old female who had splenectomy for idiopatic thrombocytopenic purpura, and was identified to have splenic tissue within left lobe of the liver during further assessment of ongoing thrombocytopenia.

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Section: Discussionmentioning

confidence: 99%

Intrahepatic splenosis after splenectomy performed for idiopathic thrombocytopenic purpura

Toktaş

Yavuz

İliklerden

et al. 2015

UCD

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“…2 An alternative probability of intrahepatic splenosis is that the splenic tissue and cells migration to the subcapsular location in the liver through the blood or lymphatic vessels after trauma. 11 In this regards, Kwok et al 12 hypothesized that the migration of erythrocytic progenitor cells through the portal vein following traumatic splenic rupture could promote intrahepatic splenosis development. The presentation of splenosis after liver injury is unusual.…”

Section: Discussionmentioning

confidence: 99%

Contribution of the single photon emission computed tomography with 99mTc red blood cells in splenosis

ntilde¹,

ntilde²,

Iglesias³

et al. 2016

Int J Res Med Sci

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“…Another mechanism of splenic tissue transplantation is splenic vein emboli or hematogenous spread of splenic pulp, which is suggested by cases of intrahepatic and intracranial splenosis (13,14). One theory suggests that splenic erythrocytic progenitor cells enter the liver via the portal vein, and then grow in response to tissue hypoxia (15). Splenosis is usually asymptomatic.…”

Section: Discussionmentioning

confidence: 99%

Pelvic splenosis mimicking ovarian metastasis of breast carcinoma: a case report

Metindir¹,

Mersin²,

Bulut³

2011

J Turkish German Gynecol Assoc

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Splenosis is the heterotopic autotransplantation of splenic tissue that usually follows traumatic splenic rupture and splenectomy. Implanted splenic tissue may give rise to a mass or masses in the chest, abdomen, or pelvis which the clinician must distinguish from benign or malignant tumors. A 38-year-old multiparous woman presented for a routine gynecological examination during breast cancer treatment. She had undergone splenectomy following traumatic splenic rupture at the age of 13. Pelvic examination revealed a left adnexal mass. Transvaginal ultrasonography showed a 39x56x40 mm diameter hyperechoic, hypervascular solid tumor on the left ovary. Total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed. The postoperative histological diagnosis was splenic tissue. Splenosis must be considered in the differential diagnosis of previosly splenectomized patients who present with unexplained masses.

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Portal vein entrance of splenic erythrocytic progenitor cells and local hypoxia of liver, two events cause intrahepatic splenosis

Cited by 54 publications

References 16 publications

Intrahepatic splenosis after splenectomy performed for idiopathic thrombocytopenic purpura

Intrahepatic splenosis after splenectomy performed for idiopathic thrombocytopenic purpura

Contribution of the single photon emission computed tomography with 99mTc red blood cells in splenosis

Pelvic splenosis mimicking ovarian metastasis of breast carcinoma: a case report

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