Portable mass spectrometry system: instrumentation, applications, and path to ‘omics analysis

Wang, Jing; Pursell, Madison E; DeVor, Amanda; Awoyemi, Olanrewaju; Valentine, Stephen J.; Li, Peng

doi:10.1002/pmic.202200112

Cited by 13 publications

(10 citation statements)

References 227 publications

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“…On the other hand, working with copious data, whatsoever, is not complete without statistical, and mathematical processing of databases. Generally speaking, MS laid a foundation for the set of "OMICS" disciplines, and many of them took shape as sciences after some new advances in the field of MS [26]. Additional advances in scientific culture and responsible innovation are called OMICS 2.0.…”

Section: "Omics"mentioning

confidence: 99%

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Mass Spectrometry-Based Techniques Towards OMICS 2.0

Šoša¹

2023

Preprint

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The literature was scoped to help place mass spectrometric (MS) platforms in the spotlight of the life sciences, as a tool of OMICS and OMICS 2.0 technologies. Moreover, today’s appliances are so handy, that they literally place a whole lab on a single chip. Methods of OMICS (and the most recently developed term OMICS 2.0) are tackled, having in mind their aptness for educational purposes, as well as their feasibility. This same topic was highlighted in many reviews that have been periodically published. The author’s initial interest was the forensic application of MS, but since these interests changed, terms such as “biosensors” were also examined, so the review included means of discovery of efficient biomarkers and clinical therapeutic targets. Aside from simply reviewing the research status and the future perspectives, this article tackles terms such as Society 5.0 and OMICS 2.0. However, within the framework of this review, physical chemistry, bioinformatics, or specific software solutions were not specifically studied. Since the topic of generating permanent collections of digital content for retrospective analysis was also reviewed, the need for loads of data – cloud storage was discussed in the context of MS. These large quantities of data are easier to operate with if generated by MS, rather than by any other commercially available assay. In this manner, the review has strengthened an in-depth understanding of the applications of MS.

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Section: "Omics"mentioning

confidence: 99%

“…In Society 5.0 application of OMICS technologies is tackled in diverse and complementary global settings. We call this concept -OMICS 2.0 [3,26,65]. This leap forward furthers the improvement of the quality of life of all people in a sustainable world [101].…”

Section: A Systematic Review Of Mass Spectrometry and Sustainability/...mentioning

confidence: 99%

Mass Spectrometry-Based Techniques Towards OMICS 2.0

Šoša¹

2023

Preprint

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show abstract

Section: "Omics"mentioning

confidence: 99%

“…In Society 5.0 application of OMICS technologies is tackled in diverse and complementary global settings. We call this concept -OMICS 2.0 [3,25]. This leap forward furthers the improvement of the quality of life of all people in a sustainability world [95] Talking specifically of MS, resulting RTs and mz can be summed, plotted and stored as a series of data acquired by modern digital instruments .…”

Section: Without Actually Knowing What Sustainability Looks Like In P...mentioning

confidence: 99%

Mass Spectrometry-Based Techniques Towards OMICS 2.0

Šoša¹

2022

Preprint

View full text Add to dashboard Cite

The literature was scoped to help place mass spectrometric (MS) platforms in the spotlight of the life sciences, as a tool of OMICS and OMICS 2.0 technologies. These methods were discussed, and their feasibility was highlighted in many reviews that have been periodically published, in addition to the most recently developed term OMICS 2.0. This author’s primary interest was the forensic application of MS, but since these interests got broadened, terms such as “biosensors” were also included. So, means of discovery of efficient biomarkers and clinical therapeutic targets were also reviewed. However, within the framework of this review, physical chemistry, bioinformatics, or specific software solutions were not specifically scoped. Aside from simply reviewing the research status and the future perspectives, this article tackles terms such as Society 5.0 and OMICS 2.0. Since the topic of generating permanent collections of digital content for retrospective analysis was reviewed, what requires loads of data – cloud storage is discussed in the context of MS. In this manner, the review has strengthened an in-depth understanding of the applications of MS. These large quantities of data are easier to operate with if generated by MS, rather than by any other commercially available assay.

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“…[23][24][25][26][27][28] In particular, by adopting the continuous atmospheric pressure interface (CAPI), the Mini-MS coupled with ambient ionization sources could greatly simplify sample preparation procedures, and make rapid on-site chemical analysis possible. [29][30][31][32][33][34] To handle the quantitative analysis of biological samples for the TDM tasks, the ambient ionization should have enough capacity to separate complex matrices in biological samples. The current state of the art is that their separation ability is still incomparable to the conventional liquid chromatography (LC) technique.…”

Section: Introductionmentioning

confidence: 99%