Portable Air Cleaners and Home Systolic Blood Pressure in Adults With Hypertension Living in New York City Public Housing

Wittkopp, Sharine; Anastasiou, Elle; Hu, Jiyuan; Liu, Mengling; Langford, Aisha T.; Brook, Robert D.; Gordon, Terry; Thorpe, Lorna E.; Newman, Jonathan

doi:10.1161/jaha.123.029697

Cited by 2 publications

(2 citation statements)

References 5 publications

(5 reference statements)

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“…Three other systematic reviews and meta-analyses on the topic of PACs and blood pressure demonstrated similar results and effect sizes. [56][57][58] Wittkopp et al 20 conducted a pilot PAC intervention trial in patients with hypertension, wherein participants ran the PAC at home and reported at-home morning blood pressure readings. In contrast, prior PAC studies relied on in-office blood pressure.…”

Section: Use Of Portable Air Cleaners Indoorsmentioning

confidence: 99%

Personal Strategies to Reduce the Cardiovascular Impacts of Environmental Exposures

Bonanni,

Newman

2024

Circulation Research

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Ubiquitous environmental exposures increase cardiovascular disease risk via diverse mechanisms. This review examines personal strategies to minimize this risk. With regard to fine particulate air pollution exposure, evidence exists to recommend the use of portable air cleaners and avoidance of outdoor activity during periods of poor air quality. Other evidence may support physical activity, dietary modification, omega-3 fatty acid supplementation, and indoor and in-vehicle air conditioning as viable strategies to minimize adverse health effects. There is currently insufficient data to recommend specific personal approaches to reduce the adverse cardiovascular effects of noise pollution. Public health advisories for periods of extreme heat or cold should be observed, with limited evidence supporting a warm ambient home temperature and physical activity as strategies to limit the cardiovascular harms of temperature extremes. Perfluoroalkyl and polyfluoroalkyl substance exposure can be reduced by avoiding contact with perfluoroalkyl and polyfluoroalkyl substance–containing materials; blood or plasma donation and cholestyramine may reduce total body stores of perfluoroalkyl and polyfluoroalkyl substances. However, the cardiovascular impact of these interventions has not been examined. Limited utilization of pesticides and safe handling during use should be encouraged. Finally, vasculotoxic metal exposure can be decreased by using portable air cleaners, home water filtration, and awareness of potential contaminants in ground spices. Chelation therapy reduces physiological stores of vasculotoxic metals and may be effective for the secondary prevention of cardiovascular disease.

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Section: Use Of Portable Air Cleaners Indoorsmentioning

confidence: 99%

Personal Strategies to Reduce the Cardiovascular Impacts of Environmental Exposures

Bonanni,

Newman

2024

Circulation Research

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“…An overview of this research can be found in a recent systematic review and meta-analysis written by our group ( 172 ). PACs may also reduce blood pressure ( 173 , 174 ). Given the importance of inflammation in CVD progression in diabetes, interventions to attenuate the upregulation of these pathways are appealing.…”

Section: An Eye Toward Preventionmentioning

confidence: 99%

A review of air pollution as a driver of cardiovascular disease risk across the diabetes spectrum

Bonanni,

Wittkopp,

Long

et al. 2024

Front. Endocrinol.

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The prevalence of diabetes is estimated to reach almost 630 million cases worldwide by the year 2045; of current and projected cases, over 90% are type 2 diabetes. Air pollution exposure has been implicated in the onset and progression of diabetes. Increased exposure to fine particulate matter air pollution (PM2.5) is associated with increases in blood glucose and glycated hemoglobin (HbA1c) across the glycemic spectrum, including normoglycemia, prediabetes, and all forms of diabetes. Air pollution exposure is a driver of cardiovascular disease onset and exacerbation and can increase cardiovascular risk among those with diabetes. In this review, we summarize the literature describing the relationships between air pollution exposure, diabetes and cardiovascular disease, highlighting how airborne pollutants can disrupt glucose homeostasis. We discuss how air pollution and diabetes, via shared mechanisms leading to endothelial dysfunction, drive increased cardiovascular disease risk. We identify portable air cleaners as potentially useful tools to prevent adverse cardiovascular outcomes due to air pollution exposure across the diabetes spectrum, while emphasizing the need for further study in this particular population. Given the enormity of the health and financial impacts of air pollution exposure on patients with diabetes, a greater understanding of the interventions to reduce cardiovascular risk in this population is needed.

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Portable Air Cleaners and Home Systolic Blood Pressure in Adults With Hypertension Living in New York City Public Housing

Cited by 2 publications

References 5 publications

Personal Strategies to Reduce the Cardiovascular Impacts of Environmental Exposures

Personal Strategies to Reduce the Cardiovascular Impacts of Environmental Exposures

A review of air pollution as a driver of cardiovascular disease risk across the diabetes spectrum

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