Port-Site Metastasis after Laparoscopic Cholecystectomy for Benign Disease

Abstract

We describe the case history of a patient presenting with a port-site metastasis from an occult pancreatic malignancy after laparoscopy for benign gallbladder disease. While port-site recurrence is well recognized after laparoscopy for malignant disease, its presentation after laparoscopy for benign disease is rare, this being only the third such case to be reported in the literature. It emphasizes that all pathology localizing to port sites after surgery should be investigated, as it may represent the earliest sign of a hitherto occult intra-abdominal malignancy.

Cutaneous Metastasis after Surgery, Injury, Lymphadenopathy, and Peritonitis: Possible Mechanisms

“…Skin metastases can develop not only at incisional scars after cancer surgery, but also at incisional scars after surgery for a benign disease performed in the presence of an undiagnosed cancer at the time of surgery. Skin metastases in patients with pancreatic and colon cancer have developed within surgical scars, where the surgery for a benign disease was performed one to twelve months before the cancer diagnosis [25,26,27,28,29]. These metastases may form by the colonization of cancer cells that are already present in the blood stream at the time of surgery for benign diseases, as these cancers tend to frequently develop hematogenous metastasis.…”

“…Skin metastases usually develop at the umbilicus, surgical scars, including laparoscopic port sites, and in the vicinity of metastatic lymph nodes [4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46]. Skin metastases are often a late manifestation of the disease; however, in certain cases they may sometimes be the first sign of internal malignancies such as lung, renal, and ovarian cancers [47].…”

A case report of wound site seeding following cholecystectomy for dysplastic gallbladder

“…We aim to focus our discussion on patients developing wound site metastasis following cholecystectomy (laparoscopic or open) for gallbladder carcinoma. The incidence of port site metastasis from gallbladder carcinoma range from 10 to 17% in the literature [2] , [3] , [4] , [5] , [6] , with the median time for recurrence at the port site following cholecystectomy being 7 months [2] . There are relatively more reports of port site recurrence in the literature and it is recognised as a form of loco-regional recurrence of the carcinoma.…”

Abdominal wall recurrence following laparoscopic surgical treatment of colorectal cancer – case report

“…It is estimated that in 2014 there were 30,660 new cases of colon and rectal cancer. 5 By being a minimally invasive procedure, the treatment of GIT cancer by videolaparoscopy has become the preferred access route in the palliative handling of advanced tumors, enabling the complementation of preoperative staging and allowing the making of intestinal diversions and resections with less risk and better postoperative outcomes. 1 It is recognized today that the oncological progress after potentially curative operations for colorectal cancer is not compromised.…”