Porphyria Cutanea Tarda in Relapse: A Case Report

Variegate Porphyria

“…These included mixed porphyria, protocoproporphyria, and PCT hereditaria. [3][4][5][6][7] VP was identified as an independent disorder in the 1950s, when an unusually high incidence of porphyria was noted in South Africa. [8][9][10][11][12] The condition was characterized by the development of severe abdominal and neurological crises but, in contrast to AIP, the disease was frequently associated with the presence of a vesiculo-erosive photodermatitis.…”

The porphyrias: a review.

“…Subsequent reports established that 'porphyria cutanea tarda' was predominantly a disease of men over the age of 40, who frequently gave a history of alcoholism and showed evidence of liver dysfunction and that both attacks of acute porphyria and a family history of porphyria were uncommon in this group (Szodoray and Sumegi, 1944;Brunsting, Mason, and Aldrich, 1951;Brunsting, 1954). However, there were also accounts of a less common cutaneous porphyria in which both photosensitivity and acute attacks occurred (Gray, Rimington, and Thomson, 1948;Watson, 1951 ;MacGregor, Nicholas, and Rimington, 1952;Rimington, 1952;Calvert and Rimington, 1953;Discombe and Treip, 1953;Wells and Rimington, 1953;Holti, Rimington, Tate, and Thomas, 1958). In general these patients were younger than the former group and in some there was evidence of porphyria in other members of the family although there was no difference between the skin lesions in the two groups.…”

The Skin and Disordered Porphyrin Metabolism

“…Meeting of the British Medical Association and the Canadian Medical Association, Edinburgh, 1959. faeces, except during exacerbations, when the urinary excretion rises at the expense of the faecal (Gray et al, 1948;Macgregor et al, 1952;Wells and Rimington, 1953;Calvert and Rimington, 1953;Holt et al, 1958). Secondly, PBG and ALA are passed, if at all, only in small amount and are most likely to be found at the height of the attack.…”