Porous Titanium Dioxide Spheres for Drug Delivery and Sustained Release

Cui, Xingang; Chen, Hua; Ye, Qing-Bang; Cui, Xinyu; Cui, Xiaojing; Cui, Hongjing; Shen, Guang-Zhi; Li, Miao-jing; Lin, Jiantao; Sun, Yongkun

doi:10.3389/fmats.2021.649237

Cited by 8 publications

(1 citation statement)

References 33 publications

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“…Polyelectrolyte assembly is conducted on a sacrificial template core that easily decomposes in basic or acid media without affecting the polyelectrolyte capsule. The core can be fabricated from carbonates (CaCO 3 , CdCO 3 , MnCO 3 ) or oxides (SiO 2 , TiO 2 ) [25][26][27]. The core can incorporate various materials (drugs, peptides, genes, or proteins) by preloading methods or can be dissolved once the capsules are fabricated, making room for drugs, peptides, genes, or proteins in so-called post-loading methods [28][29][30][31].…”

Section: Introductionmentioning

confidence: 99%

Transport of Magnetic Polyelectrolyte Capsules in Various Environments

Stavarache

Vînătoru²,

Mason

2022

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Microcapsules consisting of eleven layers of polyelectrolyte and one layer of iron oxide nanoparticles were fabricated. Two types of nanoparticles were inserted as one of the layers within the microcapsule’s walls: Fe2O3, ferric oxide, having a mean diameter (Ø) of 50 nm and superparamagnetic Fe3O4 having Ø 15 nm. The microcapsules were suspended in liquid environments at a concentration of 108 caps/mL. The suspensions were pumped through a tube over a permanent magnet, and the accumulation within a minute was more than 90% of the initial concentration. The design of the capsules, the amount of iron embedded in the microcapsule, and the viscosity of the transportation fluid had a rather small influence on the accumulation capacity. Magnetic microcapsules have broad applications from cancer treatment to molecular communication.

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