Porous Polylactide Microparticles as Effective Fillers for Hydrogels
Yuriy D. Zagoskin,
Yana E. Sergeeva,
Yuliya S. Fomina
et al.
Abstract:High-strength composite hydrogels based on collagen or chitosan–genipin were obtained via mixing using highly porous polylactide (PLA) microparticles with diameters of 50–75 µm and porosity values of over 98%. The elastic modulus of hydrogels depended on the filler concentration. The modulus increased from 80 kPa to 400–600 kPa at a concentration of porous particles of 12–15 wt.% and up to 1.8 MPa at a filling of 20–25 wt.% for collagen hydrogels. The elastic modulus of the chitosan–genipin hydrogel increases … Show more
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