Porous Carbon Produced in Air: Physicochemical Properties and Stem Cell Engineering

Abstract

A novel one‐pot in situ templating method of synthesizing micro‐ and mesoporous carbon (spheres) in oxygenic conditions is reported. The mesoporous carbon has an extremely high surface area (over 1600 m2 g−1). We also introduce, for the first time, lactate as a source of carbon, which is relatively inexpensive and bio‐friendly. To achieve this, aerosol‐based methods are employed to create a mesoporous and nanostructured carbon‐based material with the ultimate goal of influencing human stem cell biology.

A Novel Cell Penetrating Peptide for the Differentiation of Human Neural Stem Cells

“…We, in addition, utilized RA-PepB 3 to specifically test for its ability to differentiate hNSCs. We utilized human ReNcell VM (RVM, from ventral mesencephalon) cells for this latter study, which are from the midbrain (mesencephalon) area and have been recently utilized in stem cell engineering work [ 35 , 36 , 37 , 38 ].…”

Fast Conversion of Ionic Liquids and Poly(Ionic Liquid)s into Porous Nitrogen-Doped Carbons in Air

“…It is therefore a matter of scientific curiosity whether one can produce porous carbons in the presence of air. Stucky et al [ 20 ] recently reported the production of hollow, porous carbon spheres, which relied on physical confinement by a dense TiO 2 barrier shell to block the access of O 2 . In fact, physcial confinement has been applied in industrial carbonization processes carried out in sealed chambers, where oxygen is first quickly consumed by the carbon precursors, and then it becomes a process protected by the remaining N 2 .…”

Aerosol-Assisted Fast Formulating Uniform Pharmaceutical Polymer Microparticles with Variable Properties toward pH-Sensitive Controlled Drug Release

“…In aerosol methods, liquids are atomized to droplets, which are subsequently dried and/or thermally treated to obtain targeted particles [34,35,36,37]. During fast solvent evaporation, solutes in liquid droplets are driven away far from equilibrium and forced to be assembled together, leading to unique co-assembly mechanisms and boundary phenomena, and then to novel materials with unique structures, such as mesoporous, core-shell, and hierarchical structures [34,35,36,37,38,39,40,41].…”

“…Conventional aerosol techniques, such as conventional spray drying, however, often produce microparticles with relatively small sizes (typically tens of nanometers to a few micrometers) and very broad particle size distributions [34,35,36,37,38,39,40,41,42], mainly due to the atomized droplets of a wide range of size distributions and complex travelling trajectories, which experience different drying histories within the same product batch. Consequently, the effect of a particular process parameter on microparticle properties and a particular property on particle performance cannot be accurately figured out.…”