Porous alumina as potential nanostructures for drug delivery applications, synthesis and characteristics

Pourmadadi, Mehrab; Farokh, Arian; Rahmani, Elham; Shamsabadipour, Amin; Eshaghi, Mohammad Mahdi; Rahdar, Abbas; Ferreira, Luiz Fernando Romanholo

doi:10.1016/j.jddst.2022.103877

Cited by 9 publications

(4 citation statements)

References 72 publications

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“…Nanotechnology offers tremendous applications in biomedical engineering for loading therapeutic cures, specifically in cancer treatments. Thanks to their unique surface features, nanoparticles (NPs) can offer a promising platform for loading therapeutic agents in drug delivery systems [ 2 , 3 , 4 , 5 , 6 , 7 , 8 ]. The interaction of NPs with biological systems has offered the simultaneous possibility of targeted drug delivery, monitoring, and therapy.…”

Section: Introductionmentioning

confidence: 99%

Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

et al. 2022

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Nanomaterials have demonstrated a wide range of applications and recently, novel biomedical studies are devoted to improving the functionality and effectivity of traditional and unmodified systems, either drug carriers and common scaffolds for tissue engineering or advanced hydrogels for wound healing purposes. In this regard, metal oxide nanoparticles show great potential as versatile tools in biomedical science. In particular, iron oxide nanoparticles with different shape and sizes hold outstanding physiochemical characteristics, such as high specific area and porous structure that make them idoneous nanomaterials to be used in diverse aspects of medicine and biological systems. Moreover, due to the high thermal stability and mechanical strength of Fe2O3, they have been combined with several polymers and employed for various nano-treatments for specific human diseases. This review is focused on summarizing the applications of Fe2O3-based nanocomposites in the biomedical field, including nanocarriers for drug delivery, tissue engineering, and wound healing. Additionally, their structure, magnetic properties, biocompatibility, and toxicity will be discussed.

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Section: Introductionmentioning

confidence: 99%

Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

et al. 2022

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“…Bioactive ceramics hydroxyapatites coatings on metallic implants [177][178][179] fluorapatite-based composites bone applications [180] bioactive glasses bone substitute and drug carrier [181] bioactive glass ceramics chemo hyperthermia [182] Biodegradable (bioresorbable)ceramics aluminium-calcium phosphate biomedical application [183] zinc-calcium phosphorous oxides postoperative tumour treatment [184] zinc-sulfate-calcium phosphates tissue engineering [185] ferric-calcium phosphorous oxides scaffolding for cell and drug delivery [186] coralline drugs [187] calcium aluminates bioactive dental materials [188] Bioinert (nonresorbable) ceramics alumina drug delivery [189] zirconia biomedical applications [190] carbons biomedical applications for tissue engineering [191] silicon nitride biomedical applications in medical implants [192]…”

Section: Bioceramics Examples Applications Referencesmentioning

confidence: 99%

Advanced Biomedical Applications of Multifunctional Natural and Synthetic Biomaterials

Chelu,

Musuc

2023

Processes

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Biomaterials are mostly any natural and synthetic materials which are compatible from a biological point of view with the human body. Biomaterials are widely used to sustain, increase, reestablish or substitute the biological function of any injured tissue and organ from the human body. Additionally, biomaterials are uninterruptedly in contact with the human body, i.e., tissue, blood and biological fluids. For this reason, an essential feature of biomaterials is their biocompatibility. Consequently, this review summarizes the classification of different types of biomaterials based on their origin, as natural and synthetic ones. Moreover, the advanced applications in pharmaceutical and medical domains are highlighted based on the specific mechanical and physical properties of biomaterials, concerning their use. The high-priority challenges in the field of biomaterials are also discussed, especially those regarding the transfer and implementation of valuable scientific results in medical practice.

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“…This is due to their special structure and chemical properties. 41,73 Ma et al incorporated α-Al 2 O 3 nanodots into aggregates of thin-layer graphite through HEBM. These nanodots enhance the cyclic stability of graphite electrodes in lithium-ion batteries, providing a new method for large-scale preparation of fast-charging electrode materials.…”

Section: Shear-to-shock Ratiomentioning

confidence: 99%

“…In the medical field, the use of alumina has increased in the transport of drugs and in dentistry. This is due to their special structure and chemical properties 41,73 . Ma et al.…”

Section: Mechanochemical Synthesis Of Oxide Ceramic Powdersmentioning

confidence: 99%

Mechanochemical synthesis of nanostructured and composite oxide ceramics: From mechanisms to tailored properties

Zhang,

Xu,

Zhang

et al. 2023

Int J Applied Ceramic Tech

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Mechanochemical synthesis is a technology formed in the 1950s. By applying mechanical energy, mechanochemical synthesis stimulates chemical reactions, causing structural and phase changes and enabling difficult or otherwise impossible reactions to occur. Mechanochemical reactions are relatively safe, clean and efficient. At present, the synthesis of oxide ceramic materials by mechanochemical methods has attracted widespread attention. In the production of oxide ceramic materials, the characteristics of ceramic powder have a certain influence on the molding, sintering, microstructure, and mechanical properties of subsequent ceramics. In this paper, the research progress of mechanical chemistry in the synthesis of nanostructures and composite oxide ceramic powders is reviewed. The effects of process parameters such as ball milling time, speed, atmosphere, grinding media, additives, and ball‐to‐powder ratio on reaction kinetics, phase formation, and powder properties are summarized. In addition, challenges and opportunities for ceramic powder synthesis are also discussed.

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Porous alumina as potential nanostructures for drug delivery applications, synthesis and characteristics

Cited by 9 publications

References 72 publications

Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

Advanced Biomedical Applications of Multifunctional Natural and Synthetic Biomaterials

Mechanochemical synthesis of nanostructured and composite oxide ceramics: From mechanisms to tailored properties

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