Porokeratosis of Mibelli and superficial disseminated porokeratosis

Development of Segmental Superficial Actinic Porokeratosis during Immunosuppressive Therapy for Pemphigus Vulgaris

“…Although a causal relationship between immunosuppressive therapy and the development of PK is conceivable, the underlying pathophysiological mechanisms remain unclear. One hypothesis is that local or systemic immune surveillance may be reduced by immunosuppressive therapy leading to insufficient detection and elimination of aberrant keratinocyte clones ( 1 ). Recently, gene expression analysis identified up-regulation of keratin genes involved in wound healing and genes essential for epidermal differentiation (e.g.…”

“…Common to all PK is the typical histological feature ofa comoid lamella, which corresponds to the hyperkeratotic rim of slowly centriftigal spreading lesions ( 1 ). Several subtypes of PK have been distinguished based on size, localization and number of lesions.…”

A case of disseminated superficial porokeratosis associated with giant porokeratosis in pregnancy

“…Apart from these five clinical variants, a number of atypical morphological forms such as facial, giant, punched-out, hypertrophic, verrucous, and reticulate porokeratosis have also been reported in literature. [1]…”

Disseminated superficial actinic porokeratosis co-existing with linear and verrucous porokeratosis in an elderly woman: Update on the genetics and clinical expression of porokeratosis

“…[7][8][9][10][11][12][13][14][15][16][17][18] When an individual has isolated linear porokeratosis, often there are family members with DSAP. 11,19 Our patient had DSAP on the distal extremities, linear porokeratosis on the lateral thighs, and verrucous porokeratosis on the buttocks and mons pubis.…”