Porocarcinoma Detected by Fine Needle Aspiration Biopsy of a Node Metastasis

Blandamura, Stella; Altavilla, Giuseppe; C, Antonini; Marchetti, M; Piazza, Mario

doi:10.1159/000333525

Cited by 8 publications

(16 citation statements)

References 17 publications

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“…This constellation of findings was distinctive in the present case and, in the proper clinical setting, is diagnostic. Our cytologic findings are consistent with those of Blandamura et al, 3 who reported the first cytologic findings of an EP lymph node metastasis in a 65-year-old woman. Tumor cells showed clear, granular or keratinized cytoplasm and vesicular nuclei, with prominent nucleoli, and formed nests or cords, sometimes harboring central necrosis.…”

Section: Discussionsupporting

confidence: 92%

See 1 more Smart Citation

Eccrine Porocarcinoma

Bonadio

Armstrong²,

Gu³

2006

Acta Cytologica

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Section: Discussionsupporting

confidence: 92%

“…Review of the literature yielded only 1 case report on the aspiration cytology of EP, 3 and consequently the cytomorphologic characteristics of EP remain incompletely defined. This paper presents the second case of fine needle aspiration cytology of EP along with histopathology and immunohistochemistry.…”

mentioning

confidence: 99%

Eccrine Porocarcinoma

Bonadio

Armstrong²,

Gu³

2006

Acta Cytologica

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“…Our case is the third reported describing the FNA cytology of metastatic EP. 17,18 Similar to what previously described, 17,18 FNA cytology of metastatic EP in the current case revealed discohesive clusters of tumor cells and single scattered cells. A majority of the cells had dense, refractile cytoplasm.…”

Section: Discussionsupporting

confidence: 83%

Fine‐needle aspiration cytology of metastatic eccrine porocarcinoma

Olsen

Lowe

et al. 2009

Diagnostic Cytopathology

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Eccrine porocarcinoma (EP), although rare, is widely recognized as the most common malignant sweat gland tumor. EP typically grows slowly and usually is cured by surgical excision with clear margins. An elevated mortality rate, however, is observed when regional lymph nodes are involved. We herein describe cytohistologic findings in a case of metastatic EP. An 86-year-old man with a history of EP of the left lateral ankle and squamous cell carcinoma in situ (Bowen's disease) of the penis presented with enlarged left inguinal lymph nodes. A superficial fine-needle aspiration (FNA) was performed and demonstrated a hypercellular sample with discohesive clusters and/or individual tumor cells. The tumor cells were round or oval with most of the cells showing dense, refractile cytoplasm. Intracytoplasmic vacuoles were readily appreciated in some of the cells. Nuclear enlargement, high N/C ratio, nuclear hyperchromasia, bi- and multinucleation, and prominent nucleoli were seen. A diagnosis of metastatic eccrine porocarcinoma was rendered. Enlarged retroperitoneal lymph nodes were detected and CT-guided left retroperitoneal core biopsy was performed 1 week later. The biopsy revealed features consistent with metastatic eccrine porocarcinoma.

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“…There are rare reports of cytologic features before the present one. [20][21][22][23] Blandamura et al 20 observed nests and cords of malignant cells showing clear granular or keratinized cytoplasm and vesicular nuclei, with prominent nucleoli and necrosis as prominent features. 20 Clear cell eccrine carcinomas consist of cells with clear cytoplasm and prominent round or oval hyperchromatic nuclei.…”

Section: Discussionmentioning

confidence: 99%