Pore Size Distribution off "in situ" Coated Silica Gels Determined by Exclusion Chromatography

Silica monolithic columns: Synthesis, characterisation and applications to the analysis of biological molecules

“…The results obtained by SEC and mercury porosimetry are comparable. However, the pore size distribution obtained with SEC may appear somewhat broader [58,59]. SEC has the advantage of being a nondestructive method.…”

Adsorption of 1-pentanol on alkyl-modified silica and its effect on the retention mechanism in reversed-phase liquid chromatography

“…This effect is well-known from gas-liquid chromatography (16). The phenomenon of capillary condensation has explained the change in pore size distribution that occurred for silica columns coated with formamide by adsorption from dichloromethane (17) but no measurement of the adsorption isotherm of formamide was made and the effect was not correlated to the retention of solutes.…”

Evaluation of liquid chromatography column retentivity using macromolecular probes

“…In this way, enthalpic retentivity of the HPLC columns can be qualitatively evaluated and the effect of analyte size can be assessed. As a side product, both effective pore size and volume, as well as their distributions, can be estimated using the so-called inverse size exclusion chromatography [6,7]. The described procedure has been applied in the study of the interactivity of various silica C 18 phases [1][2][3].…”