“…Of these, structural protein GP5 serves as a major virulence determinant. It is the preferred protein for developing new vaccines due to its important immune domains such as neutralizing epitope, antigenic determinants, and glycosylation sites [ 15 , 16 , 17 , 18 , 19 , 20 ]. Moreover, GP5 plays a vital role not only in PRRSV infection, cell binding, and immune evasion, but also in cell apoptosis [ 21 , 22 , 23 , 24 , 25 ].…”