Porcine pericardium as glaucoma implant tube coverage: an experimental study

Pinto, Luciano Ribeiro; Regatieri, Caio V.; Tavares, Ivan Maynart; Rigueiro, Moacyr Pezati

doi:10.1590/s0004-27492008000500003

Cited by 4 publications

(2 citation statements)

References 25 publications

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“…When choosing among patch grafts, many factors must be taken into account, including availability of the material, immune reactions due to allogenic antigens, secondary infections, foreign body reactions, and inflammation. 10,31 Perichondrial graft harvested from the tragus offers many advantages. First, it is an autologous tissue, which can be harvested with local anesthesia.…”

Section: Discussionmentioning

confidence: 99%

Autologous Tragal Perichondrium Patch Graft for Ahmed Glaucoma Valve Tube Exposure

Chun

Kim

2013

Journal of Glaucoma

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Section: Discussionmentioning

confidence: 99%

Autologous Tragal Perichondrium Patch Graft for Ahmed Glaucoma Valve Tube Exposure

Chun

Kim

2013

Journal of Glaucoma

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“…The most commonly used patch grafts such as the sclera, dura, pericardium and fascia lata in repairing of scleral defects have some limitations [25-32]. Scleral or pericardial tissue grafts may induce immune rejection leading to graft failure.…”

Section: Discussionmentioning

confidence: 99%

Autologous Tragal Perichondrium Transplantation: A Novel Approach for the Management of Painful Bullous Keratopathy

Kim

Chun

Kim

2013

Korean J Ophthalmol

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PurposeTo introduce autologous tragal perichondrium transplantation as a novel surgical modality for the management of intractable symptomatic bullous keratopathy.MethodsIn three eyes of three patients with painful bullous keratopathy, autologous tragal perichondria were transplanted on the corneal surface with the human amniotic membrane transplanted above. We included an additional three eyes of three patients with painful bullous keratopathy who received amniotic membrane transplantation only to serve as controls. Clinical symptom outcomes were assessed using a visual analogue scale at postsurgical months 1, 3, 5, 7, and 9. In addition, transplanted tragal perichondrium and amniotic membrane complex tissue button obtained from one patient who underwent penetrating keratoplasty was evaluated by immunohistochemical analysis of CD34, vimentin, and alcian blue staining.ResultsAll three patients who underwent autologous tragal perichondrium and human amniotic membrane co-transplantation showed improvements in pain and tearing. However, all three patients in the control group experienced aggravation of tearing and no further improvement of pain 3 months after surgery. In addition, one patient in the control group developed premature degradation of the amniotic membrane. Histopathologic and immunohistochemical analysis showed intact surface epithelization and positive CD34, vimentin and alcian blue staining of transplanted tragal perichondria.ConclusionsThe tragal perichondrium has a high mechanical structural force and high potency due to well-organized epithelization and the presence of mesenchymal stem cells. Autologous tragal perichondrium transplantation may be an effective modality for the management of painful bullous keratopathy.

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Donor scleral graft vs pericardial graft vs scleral flap in tube drainage covering: advantages and disadvantages

Silva

Bollemeijer

Ferreira

et al. 2022

Expert Review of Ophthalmology

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Porcine pericardium as glaucoma implant tube coverage: an experimental study

Cited by 4 publications

References 25 publications

Autologous Tragal Perichondrium Patch Graft for Ahmed Glaucoma Valve Tube Exposure

Autologous Tragal Perichondrium Patch Graft for Ahmed Glaucoma Valve Tube Exposure

Autologous Tragal Perichondrium Transplantation: A Novel Approach for the Management of Painful Bullous Keratopathy

Donor scleral graft vs pericardial graft vs scleral flap in tube drainage covering: advantages and disadvantages

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