It is my function in this symposium briefly to outline some of the factors influencing the biology of the populations of social insects. Inasmuch as the social insects differ from other insects in their more complex integrated populations, it would seem to me that my discussion should place some emphasis upon the complexity of the population dynamics characteristic of these forms.At the same time, the factors which influence population biology of social insects may also play an important role at various other levels of population integration. We may thus be able to give hints to the investigator of simpler population systems, much as the vertebrate physiologist may suggest interactions occurring in the protozoan.To what extent the biology of populations of social insects may help in the understanding of ,human populations is as yet not clear (see Hogben, 1931). Pearl and Gould ( 1936, p. 418) state that "the tendency of human social organization to approach more and more closely that of the termites has been evident for a century at least; with its increasing rigid differentiation of occupational castes, its abrogations of individual liberty of action, its heavy and ever-growing burden of economic overhead service expense entailed in getting subsistence; all these being direct consequences of living under conditions of high population density." The least one can say is that the effect of social organization on population dynamics of all available social animals is an important problem which demands careful investigation.In spite of the obvious complexity of the interacting factors influencing the social insect population, I have attempted to make a simplified diagram which will illustrate some of the major factors and the direction of their effect (Figure 1). Surrounding the central population complex are arranged in concentric circles ( 1) the intraspecific societal factors, (2) the interspecific societal factors, and ( 3) the environmental factors, both physical and biotic. All these factors are divided radially into those which tend to increase the population, those which tend to decrease the population, and those which fluctuate in their effect upon increase or decrease of the numbers and types of individuals.The direction of the effect of each factor is indicated by the arrows. The arrows are pointed in both directions if there is a reciprocal interaction 1 I am indebted to Dr. W. C. Allee and to Dr. Thomas Park for many helpful suggestions.