Population Health and Aging

Morley, John E.; Sanford, Angela M.

doi:10.1007/s12603-019-1227-5

Cited by 2 publications

(2 citation statements)

References 66 publications

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“…Considering the increasing age of the population and other factors such as lifestyle (workload, stress, environmental pollution, etc. ), there is a global effort to ensure a certain standard of living, with an emphasis on the increasing level of medical care as well as on a healthy and nutritionally balanced diet [ 1 , 2 , 3 ]. Many people in developed countries suffer from obesity, a complex multifactorial disease.…”

Section: Introductionmentioning

confidence: 99%

Encapsulation: A Strategy to Deliver Therapeutics and Bioactive Compounds?

et al. 2023

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There is a growing demand for efficient medical therapies without undesired side effects that limit their application. Targeted therapies such as deliveries of pharmacologically active compounds to a specific site of action in the human body are still a big challenge. Encapsulation is an effective tool for targeted deliveries of drugs and sensitive compounds. It has been exploited as a technique that can manage the required distribution, action and metabolism of encapsulated agents. Food supplements or functional foods containing encapsulated probiotics, vitamins, minerals or extracts are often part of therapies and currently also a consumption trend. For effective encapsulation, optimal manufacturing has to be ensured. Thus, there is a trend to develop new (or modify existing) encapsulation methods. The most-used encapsulation approaches are based on barriers made from (bio)polymers, liposomes, multiple emulsions, etc. In this paper, recent advances in the use of encapsulation in the fields of medicine, food supplements and functional foods are highlighted, with emphasis on its benefits within targeted and supportive treatments. We have focused on a comprehensive overview of encapsulation options in the field of medicine and functional preparations that complement them with their positive effects on human health.

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Section: Introductionmentioning

confidence: 99%

Encapsulation: A Strategy to Deliver Therapeutics and Bioactive Compounds?

et al. 2023

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“…Current research suggests that the risk of developing a NDDs is significantly positively correlated with age 5 . According to the Global Health and Aging report presented by the World Health Organization (WHO), ‘The number of people aged 65 or older is projected to grow from an estimated 524 million in 2010 to nearly 1.5 billion in 2050’ 6 This trend will grow by 2.5% per year as the size of the ageing population increases 7 . NDDs have become the fourth leading cause of death among the elderly 8 .…”

Section: Introductionmentioning

confidence: 99%

The outcome and burden of Chinese patients with neurodegenerative diseases: A 10‐year clinical feature study

Li²,

Lin

et al. 2020

Int J Clin Pract

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Background As the Chinese population continues to age, the incidence of neurodegenerative diseases (NDDs) has increased dramatically, which results in heavy medical and economic burden for families and society. Objective The objective of this study was to evaluate NDDs in a southern Chinese hospital over a 10‐year period and examine trends in demographics, outcome, length of stay (LOS) and cost. Methods Retrospective medical records of patients from January 2010 to December 2019 were collected, including 7231 patients with NDDs (as case group) and 9663 patients without any NDDs (as control group). The information of social demographic data, admission source, reasons for admission, outcomes, LOS, and cost were extracted and analysed. Result The average hospitalisation age of the patients with NDDs is over 65 years (peak age 70‐89 years). Compared with the control group, the case group had a longer LOS and a higher cost and the numbers of patients with NDDs increased yearly from 2010 to 2019. The LOS shortened while the cost increased. Clinical features affected LOS and cost. Patients suffering from infection, abnormal blood pressure and the imbalance of water‐electrolyte homoeostasis as main reasons for admission were decreased; however, heart disease, cerebrovascular accident and mental diseases were significantly increased, the overall change trend of fracture/trauma remained stable. The rate of discharge to home care and mortality declined; discharge to other medical or community facilities increased over 10 years. Conclusion The majority of NDDs patients tended to be older. During the last 10 years from 2010 to 2019, the numbers of NDDs patients increased yearly, the trend of LOS became shortening and the cost gradually increasing. The main reasons of admission and outcomes of hospital showed different trends.

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Population Health and Aging

Cited by 2 publications

References 66 publications

Encapsulation: A Strategy to Deliver Therapeutics and Bioactive Compounds?

Encapsulation: A Strategy to Deliver Therapeutics and Bioactive Compounds?

The outcome and burden of Chinese patients with neurodegenerative diseases: A 10‐year clinical feature study

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