Population genomics supports baculoviruses as vectors of horizontal transfer of insect transposons

Gilbert, Clément; Chateigner, Aurélien; Ernenwein, Lise; Barbe, Valérie; Bézier, Annie; Herniou, Elisabeth A.; Cordaux, Richard

doi:10.1038/ncomms4348

Cited by 106 publications

(101 citation statements)

References 54 publications

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“…Although the vector of transfer remains unknown, an early study implicated a parasitic mite that feeds on the cytoplasm of early Drosophila embryos, potentially introducing foreign DNA into germline nuclei prior to cellularization (Houck et al 1991). This model is consistent with recent genomic analyses, which increasingly point to hostparasite interactions as vehicles for the horizontal transfer of TEs (Gilbert et al 2010(Gilbert et al , 2014Parisot et al 2014).…”

Section: Population Invasion and Horizontal Transfersupporting

confidence: 63%

Reexamining the P-Element Invasion of Drosophila melanogaster Through the Lens of piRNA Silencing

Kelleher¹

2016

Genetics

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Transposable elements (TEs) are both important drivers of genome evolution and genetic parasites with potentially dramatic consequences for host fitness. The recent explosion of research on regulatory RNAs reveals that small RNA-mediated silencing is a conserved genetic mechanism through which hosts repress TE activity. The invasion of the Drosophila melanogaster genome by P elements, which happened on a historical timescale, represents an incomparable opportunity to understand how small RNAmediated silencing of TEs evolves. Repression of P-element transposition emerged almost concurrently with its invasion. Recent studies suggest that this repression is implemented in part, and perhaps predominantly, by the Piwi-interacting RNA (piRNA) pathway, a small RNA-mediated silencing pathway that regulates TE activity in many metazoan germlines. In this review, I consider the P-element invasion from both a molecular and evolutionary genetic perspective, reconciling classic studies of P-element regulation with the new mechanistic framework provided by the piRNA pathway. I further explore the utility of the P-element invasion as an exemplar of the evolution of piRNA-mediated silencing. In light of the highly-conserved role for piRNAs in regulating TEs, discoveries from this system have taxonomically broad implications for the evolution of repression.

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Section: Population Invasion and Horizontal Transfersupporting

confidence: 63%

Reexamining the P-Element Invasion of Drosophila melanogaster Through the Lens of piRNA Silencing

Kelleher¹

2016

Genetics

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“…T. ni is a representative lepidopteran for studying fundamental insect physiology, biochemistry and molecular biology (Hanzlik & Hammock, ; Jones, Schelling, & Chhokar, ; Lam, McNeil, & Donly, ; Lundstrom, Liu, Kang, Berzins, & Steiner, ; Simmons, D'Souza, Rheault, & Donly, ; Wang & Granados, ). As a highly polyphagous noctuid generalist, T. ni has often been used for studying insect‐plant interactions, insect chemical ecology, insect‐microbe interactions and insect pathology (Bidart‐Bouzat & Kliebenstein, ; Fuxa, Richter, Ameen, & Hammock, ; Gilbert et al, ; Herde & Howe, ; Wang & Granados, ; Wang et al, ; Zeng, Wen, Niu, & Berenbaum, ). Trichoplusia ni has also been used as a herbovirous insect to investigate effects of environmental contanimants on agricultural ecosystems and to study tritrophic interactions among host plants, insects, and microbes (Haney et al, ; Pennington et al, ).…”

Section: Introductionmentioning

confidence: 99%

A high‐quality chromosome‐level genome assembly of a generalist herbivore, Trichoplusia ni

Chen

Yang

Tetreau

et al. 2019

Molecular Ecology Resources

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The cabbage looper, Trichoplusia ni, is a globally distributed highly polyphagous herbivore and an important agricultural pest. T. ni has evolved resistance to various chemical insecticides, and is one of the only two insect species that have evolved resistance to the biopesticide Bacillus thuringiensis (Bt) in agricultural systems and has been selected for resistance to baculovirus infections. We report a 333‐Mb high‐quality T. ni genome assembly, which has N50 lengths of scaffolds and contigs of 4.6 Mb and 140 Kb, respectively, and contains 14,384 protein‐coding genes. High‐density genetic maps were constructed to anchor 305 Mb (91.7%) of the assembly to 31 chromosomes. Comparative genomic analysis of T. ni with Bombyx mori showed enrichment of tandemly duplicated genes in T. ni in families involved in detoxification and digestion, consistent with the broad host range of T. ni. High levels of genome synteny were found between T. ni and other sequenced lepidopterans. However, genome synteny analysis of T. ni and the T. ni derived cell line High Five (Hi5) indicated extensive genome rearrangements in the cell line. These results provided the first genomic evidence revealing the high instability of chromosomes in lepidopteran cell lines known from karyotypic observations. The high‐quality T. ni genome sequence provides a valuable resource for research in a broad range of areas including fundamental insect biology, insect‐plant interactions and co‐evolution, mechanisms and evolution of insect resistance to chemical and biological pesticides, and technology development for insect pest management.

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“…Ivancevic et al (2013) showed that the LINE BovB has been horizontally transferred to several taxonomic groups as diverse as marsupials, ruminents, squamates or monotremes, through an arthropod vectors (ticks). Gilbert et al (2014) recently showed that two transposons (Mar1 and IFP2) initially found in the genome of the cabbage looper Trichoplusia ni, a moth feeding on a wide spectrum of plant species, could transpose in the genome of the baculovirus AcMNPV upon its infection of the insect. The low frequency of transposition events together with the polymorphisms of insertions sites in the 240-kbp viral genome strongly suggests that the transposition of these two families occurred very recently, which leads to hypothesize that the HTTs are concommittent with viral infection.…”

Section: Mechanisms Of Httsmentioning

confidence: 99%

Horizontal Transfers and the New Model of TE-Driven Genome Evolution in Eukaryotes

Baidouri¹,

Panaud

2015

Evolutionary Biology: Biodiversification From Genotype to Phenotype

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In this chapter, we present a new model of TE-driven genome evolution in eukaryotes. This model is based on the recent discovery of the propensity of transposable elements to be transferred horizontally among plant and animal species. We propose that the horizontal transfer of transposable elements (HTTs) is a key mechanism of long-term survival of TEs in eukaryotic genomes, by allowing TEs to escape from the silencing machinery of their host genome. We provide a description of the most recent discoveries of HTTs among plants and animals, an up-to-date description of the TE silencing pathways in eukaryotes, and some characteristics of TE biology in terms of functional impact and of response to environmental stress.

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Population genomics supports baculoviruses as vectors of horizontal transfer of insect transposons

Cited by 106 publications

References 54 publications

Reexamining the P-Element Invasion of Drosophila melanogaster Through the Lens of piRNA Silencing

Reexamining the P-Element Invasion of Drosophila melanogaster Through the Lens of piRNA Silencing

A high‐quality chromosome‐level genome assembly of a generalist herbivore, Trichoplusia ni

Horizontal Transfers and the New Model of TE-Driven Genome Evolution in Eukaryotes

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