Population genetics of 27 Y-STRs for the Yi population from Liangshan Yi Autonomous Prefecture, China

Chen, Dezhi; Lv, Meili; Huang, Yingjian; Hou, Yiping; Yu, Tao; Liang, Weibo

doi:10.1007/s00414-020-02249-5

Cited by 3 publications

(3 citation statements)

References 10 publications

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“…3C) where bordered the East China Sea, Taiwan Strait, and the South China Sea. In order to assess the degrees of differentiation of CSEH, we collected 50 778 individuals from 166 worldwide populations who belong to nine main language families [21,24,30–32,61–116]. Based on the frequencies of 27 Y‐filer Plus markers, we made a Manhattan distance‐based MDS that indicated that CSEH clustered with populations of southern China in Fig.…”

Section: Resultsmentioning

confidence: 99%

The Y‐STR landscape of coastal southeastern Han: Forensic characteristics, haplotype analyses, mutation rates, and population genetics

Fan

Zeng

et al. 2021

Electrophoresis

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The Y‐STR landscape of Coastal Southeastern Han (CSEH) living in Chinese southeast areas (including Guangdong, Fujian, and Zhejiang provinces) is still unclear. We investigated 62 Y‐STR markers in a reasonably large number of 1021 unrelated males and 1027 DNA‐confirmed father‐son pairs to broaden the genetic backgrounds of CSEH. In total, 85 null alleles, 121 off‐ladder alleles, and 95 copy number variants were observed, and 1012 distinct haplotypes were determined with the overall HD and DC values of 0.999974 and 0.9912. We observed 369 mutations in 76 099 meiotic transfers, and the average estimated Y‐STR mutation rate was 4.85 × 10–3 (95% CI, 4.4 × 10–3–5.4 × 10–3). The Spearman correlation analyses indicated that GD values (R2 = 0.6548) and average allele sizes (R2 = 0.5989) have positive correlations with Y‐STR mutation rates. Our RM Y‐STR set including 8 candidate RM Y‐STRs, of which DYS534, DYS630, and DYS713 are new candidates in CSEH, distinguished 18.52% of father–son pairs. This study also clarified the population structures of CSEH which isolated in population‐mixed South China relatively. The strategy, SM Y‐STRs for familial searching and RM Y‐STRs for individual identification regionally, could be applicable based on enough knowledge of the Y‐STR mutability of different populations.

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Section: Resultsmentioning

confidence: 99%

The Y‐STR landscape of coastal southeastern Han: Forensic characteristics, haplotype analyses, mutation rates, and population genetics

Fan

Zeng

et al. 2021

Electrophoresis

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“…From the dimensionality reduction analyses discussed above, the genetic relationships between Guangdong She and other Chinese populations were not clarified. In addition, we employed the Y-STR haplotype profiles of 42 Chinese minorities and Guangdong She to assess the population pairwise genetic distances by AMOVA ( Zhu et al, 2005 , 2006a , b , 2008 ; He and Guo, 2013 ; Shan et al, 2014 ; Luo et al, 2015 , 2019 ; Ou et al, 2015 ; Shu et al, 2015 ; Bai et al, 2016a ; Bian et al, 2016 ; Fu et al, 2016 ; Gao et al, 2016 ; Yao et al, 2016 ; Guo et al, 2017 ; Ji et al, 2017 ; Zhao et al, 2017 ; Cao et al, 2018 ; Chen et al, 2018 ; Liu Y. J. et al, 2018 ; Atif et al, 2019 ; Liu et al, 2019 ; Xie et al, 2019 ; Dezhi et al, 2020 ; Feng et al, 2020 ; Song et al, 2020 ; Tang et al, 2020 ). The pairwise R ST and the corresponding p values between Guangdong She and Chinese minority populations from five linguistically different families are displayed in Supplementary Table 7 .…”

Section: Resultsmentioning

confidence: 99%

Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups

Luo

Duan²,

et al. 2021

Front. Genet.

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Guangdong province is situated in the south of China with a population size of 113.46 million. Hakka is officially recognized as a branch of Han Chinese, and She is the official minority group in mainland China. There are approximately 25 million Hakka people who mainly live in the East and North regions of China, while there are only 0.7 million She people. The genetic characterization and forensic parameters of these two groups are poorly defined (She) or still need to be explored (Hakka). In this study, we have genotyped 475 unrelated Guangdong males (260 Hakka and 215 She) with Promega PowerPlex® Y23 System. A total of 176 and 155 different alleles were observed across all 23 Y-STRs for Guangdong Hakka (with a range of allele frequencies from 0.0038 to 0.7423) and Guangdong She (0.0047–0.8605), respectively. The gene diversity ranged from 0.4877 to 0.9671 (Guangdong Hakka) and 0.3277–0.9526 (Guangdong She), while the haplotype diversities were 0.9994 and 0.9939 for Guangdong Hakka and Guangdong She, with discrimination capacity values of 0.8885 and 0.5674, respectively. With reference to geographical and linguistic scales, the phylogenetic analyses showed us that Guangdong Hakka has a close relationship with Southern Han, and the genetic pool of Guangdong Hakka was influenced by surrounding Han populations. The predominant haplogroups of the Guangdong She group were O2-M122 and O2a2a1a2-M7, while Guangdong She clustered with other Tibeto-Burman language-speaking populations (Guizhou Tujia and Hunan Tujia), which shows us that the Guangdong She group is one of the branches of Tibeto-Burman populations and the Huonie dialect of She languages may be a branch of Tibeto-Burman language families.

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“…The Liangshan Yi Autonomous Prefecture is situated in the southern part of Sichuan, China, and it boasts the highest population of the Yi ethnic group in the nation[ 1 ]. The patient was a male of Yi ethnicity.…”

Section: Discussionmentioning

confidence: 99%

Eruptive xanthomas in a patient with severe hypertriglyceridemia: A case report

Ren,

Zhu,

Niu

et al. 2024

World J Clin Cases

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BACKGROUND Xanthomatosis, a metabolic disorder causing yellow growths (xanthomas), poses challenges in lipid metabolism. This case study introduces the first documented instance within China's Yi population, emphasizing the need to explore dietary habits and treatment strategies tailored to this specific community. CASE SUMMARY Xanthomatosis is a metabolic disorder where lipid metabolism goes awry, resulting in the development of yellowish growths called xanthomas. A male patient, 47 years of age, from China's Yi population, who is obese, visited our dermatology clinic complaining of widespread, non-painful rashes that have been present for two weeks. The patient works as a chef and has a diet that frequently includes oily and greasy foods. This case represents the initial documentation of xanthomatosis within the Yi population in China, offering a theoretical foundation for understanding dietary patterns and treatment options specific to the Yi community. CONCLUSION The first report of xanthomatosis in the Yi population in China lays a theoretical foundation for understanding Yi dietary patterns and treatment.

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Population genetics of 27 Y-STRs for the Yi population from Liangshan Yi Autonomous Prefecture, China

Cited by 3 publications

References 10 publications

The Y‐STR landscape of coastal southeastern Han: Forensic characteristics, haplotype analyses, mutation rates, and population genetics

The Y‐STR landscape of coastal southeastern Han: Forensic characteristics, haplotype analyses, mutation rates, and population genetics

Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups

Eruptive xanthomas in a patient with severe hypertriglyceridemia: A case report

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