Population-based trend analysis of laparoscopic Nissen and Toupet fundoplications for gastroesophageal reflux disease

Abstract

This is the first trend analysis in the literature reporting clinical outcomes of 873 prospectively enrolled patients undergoing Nissen and Toupet fundoplications during a 10-year period. The proportion of laparoscopic Nissen versus Toupet fundoplications remained stable over time, indicating that literature reports of the advantages of one procedure over the other had minimal influence on surgeons' choice of technique. Length of hospital stay, duration of surgery, morbidity, and conversion rate decreased over time, reflecting the learning curve. Clearly, patient outcomes have much improved during the 10-year observation period.

Surgical treatment of Gastroesophageal Reflux disease: yesterday and today

“…This approach was later considered "gold standard" in anti-reflux surgical procedures. Marked reduction of surgical trauma and significant reduction of duration of hospitalization related to the nature of this approach, contributed to significant interest of surgeons in the treatment of gastroesophageal disease, in particular in patients with coexisting cardiovascular disorders, in children and in patients with genetic defects (1,(22)(23)(24)(25)(26)(27)(28)(29)(30)(31).…”