Population-based Surveillance for Bacterial Meningitis in China, September 2006–December 2009

Abstract

Greater use of appropriate specimen collection and confirmatory laboratory testing is needed.

Meningitis caused by Neisseria Meningitidis, Hemophilus Influenzae Type B and Streptococcus Pneumoniae during 2005–2012 in Turkey

“…1,14,37 Hib and PCV-13 vaccines are already available for infants starting from two months of age in the Turkish NIP and the meningococcal vaccine for Hajj pilgrims has already been switched to conjugated quadrivalent vaccine in order to decrease carriage of the microorganism by returning pilgrims. In this study we observed a drastic decreased of Hib meningitis in Turkish children since Hib vaccine has been introduced in NIP.…”

“…1,2 Although most disease occurs in infants and young children, high incidence may be observed in healthy older children and adolescents. Despite the continuing development of new antibacterial agents, bacterial meningitis fatality rates remain high, with reported rates between 2% and 30%.…”

Clinical characteristics and etiology of bacterial meningitis in Chinese children >28 days of age, January 2014–December 2016: A multicenter retrospective study

“…However, the case fatality rate did not change and was 14.3% at that time (Thigpen et al, 2011). In China, the incidence of BM in 2006-2009 ranged from 6.95 to 22.3 cases per 100,000 population for children aged under 5 years (Li et al, 2014), and the case fatality rate was 18.42% for children under 5 years of age (Dong et al, 2004). The positive rate of pathogen detection was only 2.2% (Li et al, 2014).…”

“…In China, the incidence of BM in 2006-2009 ranged from 6.95 to 22.3 cases per 100,000 population for children aged under 5 years (Li et al, 2014), and the case fatality rate was 18.42% for children under 5 years of age (Dong et al, 2004). The positive rate of pathogen detection was only 2.2% (Li et al, 2014). Meanwhile, the penicillin resistance rate of S. pneumoniae rose sharply during those years, and multidrug-resistant S. pneumoniae appeared (Yao and Zhang, 2011).…”

Development and validation of an advanced fragment analysis‐based assay for the detection of 22 pathogens in the cerebrospinal fluid of patients with meningitis and encephalitis

“…According to population-based studies in China, the incidence of acute bacterial meningitis ranges from 12.4 to 19.2 cases/100 000 for children aged <5 years. [9][10][11] The primary pathogens of bacterial meningitis are Neisseria meningitidis, H. influenza, and Streptococcus pneumonia. [12][13][14] China has the second-highest prevalence of tuberculosis (TB) infection worldwide.…”