Population-Based Study of Prevalence of Cleft Lip/Palate in Southern Thailand

Jaruratanasirikul, Somchit; Chicharoen, Vichai; Chakranon, Manunya; Sriplung, Hutcha; Limpitikul, Wannee; Dissaneevate, Pathikan; Intharasangkanawin, Nitthakarn; Tantichantakarun, Pongsak; Sattapanyo, Atchara

doi:10.1597/14-259

Cited by 8 publications

(3 citation statements)

References 22 publications

(44 reference statements)

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“…But the most common forms of syndromic oral clefts are Van der Woude syndrome and 22q11.2 deletion syndrome ( Burg et al, 2016 ). In this study many patients with syndromic OFCs showed some of these conditions, as observed in previously reports ( Jaruratanasirikul et al, 2016 ).…”

Section: Discussionsupporting

confidence: 90%

How are people with orofacial clefts attended in northwest region of São Paulo state, Brazil?

Francisquetti,

Gil-da-Silva-Lopes,

Fett-Conte

2023

Genet. Mol. Biol.

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Characterization of specific birth defects is essential for conducting scientific investigations, care and therapeutic strategies. This article describes demographic, clinical and genetic aspects, risk factors and access to treatment of Brazilian patients with orofacial clefts registered in a specialized collaborative center of the Brazilian Database on Craniofacial Anomalies (BDCA). We interviewed 70 individuals with typical orofacial clefts using a standard instrument from the database and subjected them to genetic testing. The patients were grouped as syndromic and non-syndromic. The majority of individuals were of lower middle class, native ancestry and syndromic. There was a significant difference in the type of clefts regarding gender. There was no significant difference between bilateral and unilateral, between the side affected, right and left, or familial recurrence related to type of oral cleft. The risk factor familial recurrence was significantly higher among non-syndromic cases. Etiological factors were identified or suggested in 62.5% of the syndromic cases. There was a delay in diagnosis and in access to treatment in most cases. We concluded that gender, native ancestry and low family income represent risk factors. Furthermore, the distribution by cleft types and gender is similar to previous studies. The results can guide scientific investigations and care policies.

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Section: Discussionsupporting

confidence: 90%

How are people with orofacial clefts attended in northwest region of São Paulo state, Brazil?

Francisquetti,

Gil-da-Silva-Lopes,

Fett-Conte

2023

Genet. Mol. Biol.

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“…The central region has the particularity of having mainly cases with low severity (PC) or medium (CL), while the southeast region has the most severe cases (CLP), accentuating CLPu over CLPb, as reported in the literature. [32][33][34] Then, Bogotá has been reported as the most important reference center for health care in the country, the CL/P population migrates internally in search of care and better technology.…”

Section: Discussionmentioning

confidence: 99%

Population Prevalence and Trends of Oral Clefts in Colombia: Analysis by Departments

Reina

Brigetty

Salomón

2022

The Cleft Palate Craniofacial Journal

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Determine the population prevalence and trends of cleft lip and/or palate (CL/P) by department for Colombia in the period 2009 to 2015. Prevalence study based on Individual Registry of Health Services in general population from 2009 to 2015. All people diagnosed with CL/P were included for all ages, type of diagnosis, and any type of health services in the mentioned period. The prevalence was calculated by period and point for each year, for each department and according to the type of cleft. Stationarity on time series was evaluated using (Dickey-Fuller) and (Phillips-Perron). A trend test was applied to estimate whether the increase in prevalence was significant in the period. The trend test used was a Poisson regression. A total 15 225 people with CL/P were identified, where 53.3% were men. The national period prevalence of CL/P is 3.37 per 10 000 with upward trend (prevalence ratio = 1.34, P = .05) and nonstationary behavior. The national period prevalence of cleft lip is 0.93 per 10 000, cleft palate 1.17 per 10 000, and cleft lip and palate (CLP) 1.26 per 10 000, where CLP is subclassify into unilateral CLP (0.83 per 10 000) and bilateral CLP (0.43 per 10 000). At the departmental level, the highest CL/P prevalence is Guaviare (11.2), followed by Guainía (8.4) and the lowest Quindío (0.49). In Colombia, the national period prevalence of CL/P is 3.37 per 10 000 with upward trend at national level indicates an increase in prevalence from 2009 to 2015. The 77% of the total CL/P population are infant or adolescent. Geographically, the central region has the highest availability of technologies.

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“…7,21 In Saudi Arabia, a prevalence at birth rate of 0.65 per 1000 live births was reported 22 ; in Iran, 1.9 per 1000 live births 23 ; and in Thailand, 1.44 per 1000 live births. 24 The variability in estimates may be due to multiple causes, including different methods, and racial and environmental differences in populations. 20 Importantly, studies using nationally reported data come from countries with more advanced surveillance and coverage systems.…”

Section: Discussionmentioning

confidence: 99%

Trends in Cleft lip and/or Palate Prevalence at Birth in Mexico: A National (Ecological) Study Between 2003 and 2019

Cerón-Zamora

Scougall‐Vilchis

Contreras‐Bulnes

et al. 2022

The Cleft Palate Craniofacial Journal

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Objective To describe trends in cases and prevalence at birth rates of cleft lip and/or palate (CL/P) in Mexico between 2003 and 2019. Design Ecological study. Setting Multiple data sources systematically collected into a national epidemiological surveillance data warehouse. Participants National Live Birth Information System. Main Outcome Measure(s) Both cases and prevalence at birth rates of CL/P in Mexico within a 17-year period were used as dependent variables. Results At the national level there were 23 184 new cases of CL/P (average of 1364 per year) in the 32 states of Mexico, with an average prevalence at birth rate of 0.53 per 1000 live births. The states with the highest prevalence at birth rates of CL/P during the period were Hidalgo (1.59) and Jalisco (1.32), while the states with the lowest rates were Nayarit (0.22) and Durango (0.29). A slight decrease in both cases (z = −2.41, P = .016) and prevalence at birth rates (z = −2.58, P = .010) of CL/P was observed at the national level. States such as Durango, Puebla, Chiapas, Guerrero, Oaxaca, Mexico City, State of Mexico, Coahuila and Jalisco showed a clear downward trend ( P < .05) in their prevalence at birth of CL/P between 2003 and 2019, while in Hidalgo its trend was upward ( P = .05). Significant differences by sex and region were observed ( P < .05). Conclusion Some states consistently had the highest or lowest prevalence of CL/P. Decreasing trends in the overall prevalence at birth rates were observed. More detailed, epidemiological studies are necessary to adequately characterize CL/P in the Mexican population.

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Population-Based Study of Prevalence of Cleft Lip/Palate in Southern Thailand

Abstract: The prevalence of oral clefts was 1.44 per 1000 live births, with 15% of cases having an associated congenital anomaly or a recognized syndrome. Increased maternal age was associated with a higher prevalence of syndromic cleft.

Cited by 8 publications

References 22 publications

How are people with orofacial clefts attended in northwest region of São Paulo state, Brazil?

How are people with orofacial clefts attended in northwest region of São Paulo state, Brazil?

Population Prevalence and Trends of Oral Clefts in Colombia: Analysis by Departments

Trends in Cleft lip and/or Palate Prevalence at Birth in Mexico: A National (Ecological) Study Between 2003 and 2019

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