Population-based study: breast cancer mortality trend in women in the state of Paraná from 2000 to 2017

Abstract

Objective: Breast cancer is one of the main challenges in Brazilian public health due to the high associated mortality. Mortality has different patterns according to age group, usually increasing with age. The demographic stability in Paraná, with the growth of the elderly population, has a direct impact on the epidemiology of this disease. This study aimed to assess, on a population-based basis, the rates and trends of mortality from breast cancer among the age groups of women in the state of Paraná from 2000 to 2017. Methods: A statistical descriptive retrospective series study was carried out to analyze, on a population-based basis, the trend in breast cancer mortality rates among the age groups of women in the state of Paraná, from 2000 to 2017. The trend analysis of annual mortality rates was carried out through the software and simple linear regression models. Results: The population-based analysis showed that women aged 45–54 and 55–64 years had the highest number of deaths during the study period. However, when calculating the mortality rates by age group, it was observed that the mortality pattern increases proportionally to the longevity of the female population in the state. Trend analyses indicated an upward trend in mortality among women aged 25–34 years throughout the study period. The same trend was observed in women aged 35–44 years, but in a shorter period, from 2005 to 2017. Conclusion: Mortality rates, per 100,000 women, were directly proportional to age, increasing with age, indicative of greater mortality from the disease in elderly women. There was a trend of increasing mortality, with statistical significance, in the age groups from 25 to 34 and 35 to 44. The others were considered stable trends.

Correlation Between the Incidence of Breast Cancer and the Human Development Index

“…According to the World Health Organization (WHO), in the 1960s and 1970s there was a 10-fold increase in age-adjusted incidence rates in population-based breast cancer records from several continents. Estimates of new cases of breast cancer for 2018 were 59,700, representing 29.5% of cases of neoplasms in women [6]. The Human Development Index (HDI) is a measure composed of health, education and income indicators.…”