Population-Based Perspective of Long-Term Outcomes After Surgical Repair of Partial Atrioventricular Septal Defect

Partial atrioventricular septal defect in the fetus: diagnostic features and associations in a multicenter series of 30 cases

“…Our data confirm a strong association between pAVSD and chromosomal abonormalities, though to a lesser extent than that shown by complete AVSD3–5. Overall, the 29.1% association rate found in our study is similar to the 34.7% and 24.8% association rates with Down syndrome reported in two large postnatal series9, 10. However, the range of chromosomal anomalies differs in comparison with these previously reported series.…”

“…In fact, considering the association with Down syndrome only and excluding the six cases referred because they were known to have trisomy 21, among the remaining 24 cases in our series there were three cases of trisomy 21 detected prospectively. This yields an association rate of 12.5%, a figure considerably lower than that reported in the two large postnatal series9, 10. A likely explanation for the different association rates of different kinds of anomaly is selection bias: some of the cases with lethal chromosomal anomalies (e.g.…”

Congenital Heart Disease in the Older Adult

“…Overall freedom from reintervention at 10 years may be as low as 67.2% or as high as 86% 17 or 89%. 18 Independent risk factors for need for reoperation may include associated cardiovascular anomalies (P<0.001), left AV valve dysplasia (P<0.001), and nonclosure of the cleft (P=0.027) or primary cleft closure rather than patch augmentation. Survival is higher after left AV valve repair than after replacement (P=0.010), and cardiomyopathy may be more likely after replacement; however, both repair and replacement are associated with a high incidence of reoperation.…”

A Retrospective Analysis of Mid-Term Paitent Follow-ups After Partial Atrioventricular Septal Defect Repair: A Unicenter Experience

“…Özellikle atrioventriküler kapak yetmezlikleri, konjestif kalp yetmezliği, aritmiler ve sol ventrikül çıkım yolu darlıkları bunlardan başlıcalarıdır (3,(5)(6)(7)(8)(9)(10)(11)(12)(13) . Çeşitli nedenler arasında en sık reoperasyon gereksinimi ise sol AV kapak yetmezliği olarak bildirilmiştir (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) . Bu hasta grubunda Trizomi 21 bulunmayışı, ameliyat öncesi ciddi sol AV kapak yetmezliği, erken operatif yaş, kleftin kapatılmaması ve paraşüt ya da çift orifisli kapak yapısı bilinen risk faktörleridir (8,(10)(11)(12)(13) .…”