Background
Uveal melanoma is a rare type of melanoma. Most of them occur in the choroid, and a few may be found in the iris and ciliary body. The management of localized melanoma can be divided into globe-preserving therapy or enucleation. We report a case of melanoma arising from the iris and ciliary body combined with aplastic anaemia, which was successfully treated by local resection of the tumor and achieved favorable visual outcome.
Case presentation
A 31-years-old man presented with repeated episodes of Painful visual loss in his right eye for 4 years. He was diagnosed with aplastic anaemia ten years ago. Slit lamp examination showed anterior synechia, keratoleukoma and a mass in both of the anterior and posterior chamber. The IOP of right eye was elevated. Based on clinical examination: Ultrasound Biomicroscopy B-scan ultrasonography, Computerized Tomography, a presumed diagnosis of iris and ciliary body tumor and secondary glaucoma was made. The patient underwent local excision of the mass. Histopathological examination of the resected material showed a melanoma. Postoperatively, the best corrected visual acuity was improved and there was no recurrence of the tumor at the end of 7 years’ follow-up.
Conclusions A Giant iris and ciliary tumor was successfully treated by local resection, with favorable visual outcome and no recurrence for 7 years follow up. Melanoma can be differentiated from other iris and ciliary body tumors by immunohistochemical examination.