“… 3 Approximately 46 cases have been reported in the orthopedic literature until 2015. 1 , 2 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 Nonetheless, the infrequency of these complications may make the diagnosis and treatment extremely challenging to surgeons, and limb-threatening ischemia may occur subsequently. 3 , 4 We report a case of acute vascular occlusion in the midpiece of femoral artery following TKA while aggressive thrombolysis and thrombectomy could not restore arterial circulation of the lower limb, and discuss the possible etiology causes.…”