Popliteal artery entrapment syndrome (PAES) is a rare vascular disorder defined as compression of the popliteal artery by aberrant myotendinous structures in the popliteal fossa. PAES was first identified by Stuart, a medical student in 1879, who noted an anomalous course of the popliteal artery medial to the medial gastrocnemius muscle in an amputated leg (1). PAES often presents as exertional claudication in a young, otherwise healthy individual. These atypical symptoms should raise suspicion and prompt diagnostic workup. While uncommon, early diagnosis of PAES is crucial to prevent chronic vascular injury resulting in arterial stenosis, thrombosis, and possible amputation (2).
Anatomy and pathophysiologySymptoms of PAES arise from the compression of the neurovascular bundle within the popliteal fossa by the surrounding musculotendinous structures. Popliteal vein and/or tibial nerve compression may exist alone or in combination with arterial pathology (3). The syndrome exists in six forms, divided into two categories: anatomic/ congenital and functional. Anatomic PAES results from abnormal embryological development of the popliteal artery, gastrocnemius muscle, or other myofascial structures