Poor sleep and depression are independently associated with a reduced pain threshold. Results of a population based study

Chiu, Yee; Silman, Alan J.; Macfarlane, Gary J.; Ray, David; Gupta, Anindya; Dickens, Chris; Morriss, Richard; McBeth, John

doi:10.1016/j.pain.2005.03.009

Cited by 152 publications

(105 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These were chosen a priori based on previous research findings (Chiu et al., 2005; Phillips et al., 2010; Gerrits et al., 2014; Walton et al., 2013). …”

Section: Methodsmentioning

confidence: 99%

A population‐based, incidence cohort study of mid‐back pain after traffic collisions: Factors associated with global recovery

Johansson

Boyle

Hartvigsen

et al. 2015

European Journal of Pain

View full text Add to dashboard Cite

BackgroundTraffic collisions often result in a wide range of symptoms included in the umbrella term whiplash‐associated disorders. Mid‐back pain (MBP) is one of these symptoms. The incidence and prognosis of different traffic injuries and their related conditions (e.g. neck pain, low back pain, depression or others) has been investigated previously; however, knowledge about traffic collision‐related MBP is lacking. The study objectives were to describe the incidence, course of recovery and prognosis of MBP after traffic collisions, in terms of global self‐reported recovery.MethodsLongitudinal data from a population‐based inception cohort of all traffic injuries occurring in Saskatchewan, Canada, during a 2‐year period were used. Annual overall and age‐sex‐specific incidence rates were calculated, the course of recovery was described using the Kaplan–Meier technique, and associations between participant characteristics and time‐to‐self‐reported recovery were explored in 3496 MBP cases using Cox proportional hazards models.ResultsThe yearly incidence rate was 236 per 100,000 population during the study period, and was highest in women and in young persons. The median time‐to‐first reported recovery was 101 days (95% CI: 99–104) and about 23% were still not recovered after 1 year. Participant's expectation for recovery, general health, extent of severely affecting comorbidities and having experienced a previous traffic injury were some of the prognostic factors identified.ConclusionsThese findings show that MBP is common after traffic collisions, may result in a long recovery process and that a range of biopsychosocial factors are associated with recovery.

show abstract

“…These were chosen a priori based on previous research findings (Chiu et al., 2005; Phillips et al., 2010; Gerrits et al., 2014; Walton et al., 2013). …”

Section: Methodsmentioning

confidence: 99%

A population‐based, incidence cohort study of mid‐back pain after traffic collisions: Factors associated with global recovery

Johansson

Boyle

Hartvigsen

et al. 2015

European Journal of Pain

View full text Add to dashboard Cite

show abstract

“…stress, anxiety, depression, negative and positive mood) [12]. For instance, depression is independently associated with a reduced pain threshold [13]. A recent study, which examined pressure pain thresholds in similar patients, revealed that sensitivity to pressure was associated with depression, but not with multiple somatoform symptoms [14; Table 1].…”

Section: Accepted M Manuscript 11mentioning

confidence: 99%

Hypersensitivity and hyperalgesia in somatoform pain disorders

Egloff

Cámara

Känel

et al. 2014

General Hospital Psychiatry

View full text Add to dashboard Cite

Objective: In psychiatry, pain disorders not explained by structural lesions have been classified for decades as somatoform pain disorders, the underlying concept being somatization. In a parallel move, somatic medicine has defined an expanding group of similar pain disorders, known as functional pain syndromes. Functional pain syndromes are characterized by enhanced pain sensitivity. The aim of our study was to investigate the proportion of patients with somatoform pain disorders who also meet the criteria of functional pain syndromes and the extent to which patients with somatoform pain disorders also show enhanced pain sensitivity.Methods: Data on pain sensitivity in 120 hospitalized patients were obtained by means of two algometric methods. The group of patients with somatoform pain disorders was further divided into two subsets: patients with and those without a co-diagnosis of a functional pain syndrome. Patients with nociceptive pain served as control group.Results: Of the 120 in-patients selected, 67 fulfilled the criteria of a somatoform pain disorder of which 41 (61%) also met the co-diagnosis of a functional pain syndrome. Patients with somatoform pain disorder differed from controls in that they showed enhanced pain sensitivity, irrespective of whether a functional pain syndrome was concomitantly present (p<0.001).Conclusions: Somatoform pain disorders show considerable overlap with functional pain syndromes, including enhanced pain sensitivity. This suggests the relevance of integrating somatosensory aspects of pain into a modified understanding of somatoform pain disorders. A C C E P T E D M A N U S C R I P TACCEPTED MANUSCRIPT 3 BackgroundFor decades, pain disorders not or not adequately explained by structural somatic injury (or any other physiological processes such as inflammation) have been classified as somatoform pain disorders especially if they occur in the context of depression, anxiety disorders, or psychosocial stress. Under the DSM-IV section on somatoform disorders, somatoform pain disorder is defined as "pain disorder associated with psychological factors" (307.80) [1]. In its definition of 'persistent somatoform pain disorder' (F45.40), ICD-10 even explicitly attributed a causal significance to the psychological factors [2]. The rationale of DSM-IV and ICD-10 in categorizing somatoform pain disorders relies on the traditional concept of somatization. In the psychoanalytical theory, somatization was conceived as an experience of "bodily symptoms" caused by (repressed) psychological distress. As a consequence, somatoform pain disorders were classified as "mental disorders". Patients, therefore, were referred to psychiatric care.In a parallel move, somatic medicine defined an increasing group of so-called functional somatic syndromes [3,4] or, more specifically functional pain syndromes [5]. In 1990, The American College of Rheumatology, for instance, recognized fibromyalgia as a clinical entity. For the first time, hyperalgesia (with respect to the tender points) was proposed ...

show abstract

“…For example, participants with depression as a secondary diagnosis were not excluded, nor were the degree of depression or anxiety measured and controlled for statistically. It has been shown in one earlier study that depression is associated with a reduced pain threshold [18].…”

Section: Discussionmentioning

confidence: 93%

“…One previous study on sleep deprivation has shown an association between sleep deprivation and decreased pain thresholds [18]. However, another study has shown no effect on thermal, cold, or pressure pain thresholds when individuals were deprived of sleep [19].…”

Section: Discussionmentioning

confidence: 97%

Increased deep pain sensitivity in persistent musculoskeletal pain but not in other musculoskeletal pain states

Gunnarsson

Grahn

Agerström

2016

Scandinavian Journal of Pain

View full text Add to dashboard Cite

AbstractBackgroundPressure pain thresholds (PPTs) in a non-painful body area are known to be affected in some chronic pain states. The aim of this study is to investigate PPTs in a pain-free body part in relation to pain persistence and intensity in patients with musculoskeletal pain.MethodsPatients with musculoskeletal pain were divided into three different pain groups: acute pain (pain duration < 3 months, n = 38), regularly recurrent pain (regularly recurrent pain duration > 3 months, n = 56), persistent pain (persistent pain duration >3 months, n = 52) and a healthy control group (n = 51). PPT measures were conducted over the tibialis anterior muscle on the right leg in all groups.ResultsThe persistent pain group showed significantly lower PPTs over the tibialis anterior muscle compared to controls. No significant differences were found between the acute and regularly recurrent pain groups compared to healthy controls. Significant correlations, albeit small, were found between pain intensity and PPTs.ConclusionsIncreased deep pain sensitivity was found in patients with persistent musculoskeletal pain, but not in regularly recurrent pain or in acute pain. Yet, a limitation of the study is that it did not have sufficient power to detect small levels of increased deep pain sensitivity among the latter groups when compared to healthy controls.ImplicationsKnowledge about increased general hypersensitivity in persistent musculoskeletal pain could be important in clinical treatment.

show abstract

Poor sleep and depression are independently associated with a reduced pain threshold. Results of a population based study

Cited by 152 publications

References 19 publications

A population‐based, incidence cohort study of mid‐back pain after traffic collisions: Factors associated with global recovery

A population‐based, incidence cohort study of mid‐back pain after traffic collisions: Factors associated with global recovery

Hypersensitivity and hyperalgesia in somatoform pain disorders

Increased deep pain sensitivity in persistent musculoskeletal pain but not in other musculoskeletal pain states

Contact Info

Product

Resources

About