Pooled analysis of 163 published tuberculous peritonitis cases from Turkey

doi:10.3906/sag-1701-32

Cited by 6 publications

(3 citation statements)

References 32 publications

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“…In their series, 14 of 790 patients on CAPD were diagnosed with peritoneal TB between 1994 and 2000 [16]. CAPD has a strong association with developing TBP in the United States and similar studies have been reported from Taiwan and Turkey as well [9, 17]. We diagnosed two cases of CAPD peritonitis by culture in our cohort and both required removal of catheter.…”

Section: Discussionsupporting

confidence: 62%

Acid fast bacillus smear, mycobacterial culture and Xpert MTB/RIF assay for the diagnosis of tuberculous peritonitis in patients with and without end stage renal failure

Misra

Kar

Mohindra

et al. 2022

Access Microbiology

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Introduction. Diagnosis of tuberculous peritonitis (TBP) requires a high index of suspicion. Hypothesis /gap statement. Information about the diagnostic features of TBP among patients with end-stage renal failure (ESRF) from India is limited. Aim. To assess the utility of the Gene Xpert MTB/RIF assay in the diagnosis of TBP in patients with end-stage renal failure (ESRF), compared with those without ESRF. Methodology. This prospective observational single centre cohort study was performed at a tertiary care centre in Northern India. Ascitic fluid and/or whole continuous ambulatory peritoneal dialysis (CAPD) bag with effluent from 300 clinically suspected cases of TBP were included in the study. Diagnosis was based on detection of Mycobacteria on smear, Xpert MTB/RIF assay and/or culture. Cell counting was done in a Neubauer chamber. Cell predominance was seen by Giemsa stain. Line probe assay (LPA) for drug susceptibility testing was performed on all positive cultures. Results. TBP was diagnosed in 168 cases. Diabetes mellitus was a significant risk factor for developing TBP in patients with ESRF (P value<0.01). Lymphocytic predominance was seen in 21 patients without ESRF (P value 0.033) while majority of the patients in both groups had neutrophils in their ascitic and peritoneal fluids (138/168; P value 0.033). We recovered 15 cases of laboratory diagnosed TBP (11 without ESRF and four with ESRF). Microscopy was positive in two cases while ten isolates were recovered on culture. The Xpert MTB/RIF assay was positive in seven ascitic fluid samples out of which three were rifampicin resistant. All these were patients without renal failure (P value 0.010). Eight culture positive samples tested by the line probe assay did not detect any resistance to either rifampicin or isoniazid. Conclusion. The GeneXpert MTB/RIF assay has a limited value in the diagnosis of TBP in patients with ESRF.

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Section: Discussionsupporting

confidence: 62%

Acid fast bacillus smear, mycobacterial culture and Xpert MTB/RIF assay for the diagnosis of tuberculous peritonitis in patients with and without end stage renal failure

Misra

Kar

Mohindra

et al. 2022

Access Microbiology

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“…For example, the symptoms of abdominal tuberculosis consisted of abdominal swelling, abdominal pain, abdominal mass, weight loss, fever, and ascites. [13][14][15] Meanwhile, central nervous system tuberculosis usually involves fever, headache, altered mental status, and neurological deficits. 16 We believe this case report demonstrates difficulties in diagnosing abdominal tuberculosis.…”

Section: Discussionmentioning

confidence: 99%

Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature

Rinaldi¹,

Muthalib²,

Gosal³

et al. 2022

IMCRJ

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Tuberculosis (TB) is a disease with high morbidity and mortality resulting from infection by Mycobacterium tuberculosis. TB can disseminate to any organ system of the body resulting in extrapulmonary tuberculosis. Interestingly, CA-125, which is a biomarker for some cancer, also rises in benign diseases such as pulmonary and extrapulmonary tuberculosis which may complicate diagnosis. In this case report, we present an abdominal tuberculosis patient that was initially presented as ovarian cancer. Case Report: A 30-year-old woman admitted to the emergency department with chief complaint of fatigue and shortness of breath since 3 months ago. She had lost around 20 kg weight in the past 5 months. She was previously suspected with ovarian cancer because of the characteristic features of malignancy, high levels of CA-125, and positive PET scan. She was later diagnosed with abdominal TB. Subsequently, the patient was given anti-TB drugs, and the patient showed clinical improvement. Conclusion:In the case of an elevated CA-125, clinicians should consider extrapulmonary TB as a differential diagnosis of ovarian cancer, especially in countries with high burden of tuberculosis.

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“…La prueba de tuberculina (purified proteic derivate, PPD), tiene un valor limitado por su baja especificidad 30 , como también menor sensibilidad en el contexto clínico de inmunosupresión 31 y en las formas extrapulmonares; finalmente un resultado negativo no descarta la infección 32 .…”

Section: Discussionunclassified

Peritonitis tuberculosa en un niño

Arriagada¹,

Neumann

Donoso³

2019

Rev. chil. infectol.

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Pediatric tuberculous peritonitis. Case reportTuberculous peritonitis is an uncommon entity in the infant population. It is an uncommon form of extrapulmonary tuberculosis and represents a very low percentage of all cases of tuberculosis. Its symptoms are nonspecific and usually manifesting with ascites, abdominal pain, fever and low weight. The delay in its diagnosis and treatment, originated by its form of presentation, can cause an increase in its morbidity and mortality. We report the case of a 14-year-old patient without concomitant disease or pulmonary tuberculosis, who presented with ascites and fever. Laparoscopy showed multiple nodules in the abdominal cavity compatible with peritoneal tuberculosis, which was subsequently confirmed by culture and molecular test. The patient completed her antituberculosis treatment recovering satisfactorily.

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Pooled analysis of 163 published tuberculous peritonitis cases from Turkey

Cited by 6 publications

References 32 publications

Acid fast bacillus smear, mycobacterial culture and Xpert MTB/RIF assay for the diagnosis of tuberculous peritonitis in patients with and without end stage renal failure

Acid fast bacillus smear, mycobacterial culture and Xpert MTB/RIF assay for the diagnosis of tuberculous peritonitis in patients with and without end stage renal failure

Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature

Peritonitis tuberculosa en un niño

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