Pontine cavernoma haemorrhage at 24 weeks of pregnancy that resulted in eight-and-a-half syndrome

Maier, Smaranda; Moţăţăianu, Anca; Bajkó, Zoltán; Romaniuc, Anatole; Bălaşa, A

doi:10.1007/s13760-019-01147-x

Cited by 13 publications

(6 citation statements)

References 4 publications

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“…In addition to cognitive tests, the current diagnostic methods rely on imaging techniques [24][25][26][27] and cerebrospinal fluid (CSF) assays. On one hand, the purpose of the neuroimaging methods is assessing the hippocampal atrophy through magnetic resonance imaging and the cortical Aβ deposition through positron emission tomography.…”

Section: Introductionmentioning

confidence: 99%

Body Fluid Biomarkers for Alzheimer’s Disease—An Up-To-Date Overview

2020

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Neurodegeneration is a highly complex process which is associated with a variety of molecular mechanisms related to ageing. Among neurodegenerative disorders, Alzheimer’s disease (AD) is the most common, affecting more than 45 million individuals. The underlying mechanisms involve amyloid plaques and neurofibrillary tangles (NFTs) deposition, which will subsequently lead to oxidative stress, chronic neuroinflammation, neuron dysfunction, and neurodegeneration. The current diagnosis methods are still limited in regard to the possibility of the accurate and early detection of the diseases. Therefore, research has shifted towards the identification of novel biomarkers and matrices as biomarker sources, beyond amyloid-β and tau protein levels within the cerebrospinal fluid (CSF), that could improve AD diagnosis. In this context, the aim of this paper is to provide an overview of both conventional and novel biomarkers for AD found within body fluids, including CSF, blood, saliva, urine, tears, and olfactory fluids.

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Section: Introductionmentioning

confidence: 99%

Body Fluid Biomarkers for Alzheimer’s Disease—An Up-To-Date Overview

2020

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“…Globalize your Research centers with a multidisciplinary team that includes representatives for neurology, neurosurgery, obstetrics/gynaecology and anesthesiology [6]. In line with this recommendation, our patient was managed conservatively with a mutidisciplianary team management approach.…”

Section: Auctoresmentioning

confidence: 78%

A Rare Successful Multidisciplinary Team Management of Pontine Hemorrhage in Third Trimester of Pregnancy: A Case Report

Sium¹

2021

IJCCR

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“…In case of FPCAs, the ICAs must deliver a higher debit of blood than in the normal arrangement of the polygon. Patients with ICA obstruction associated with full FPCAs are exposed to a higher risk for ischemic issues, compared to patients with a normal configuration of the circle of Willis, in which the collaterals can expand between the anterior and posterior cerebral circulation [ 29 , 30 , 31 ]. Furthermore, the lack of contralateral A1 segment exposes patients to an even greater risk, considering that a single ICA must feed with blood the areas of anterior, MCA and PCA.…”

Section: ⧉ Discussionmentioning

confidence: 99%

Atypical posterior circulation strokes: a case-based review of rare anatomical variations involved

Roman-Filip

Stîngaciu²,

Catană³

et al. 2021

Rom J Morphol Embryol

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The circle of Willis is a very important vascular mechanism of protecting against cerebral ischemia, especially when circulation within the main arteries irrigating the brain is somehow impeded. As result of congenital malformation arising early in embryonic development, the fetal-type posterior circle of Willis remains as such during the rest of one's life. Consequently, the posterior cerebral artery (PCA) becomes a branch of the internal carotid artery (ICA), rather than of the basilar artery (BA). Furthermore, the rest of collateral circulation, between the anterior and the posterior regions of the brain, is also negatively affected (e.g., leptomeningeal vessels). The anatomical variant represented by the artery of Percheron (AOP) has its origin on one of the PCAs, supplying singlehandedly both paramedian areas of the thalamus (right and left) and posterior regions of the midbrain. In the present study, we report a case of bilateral thalamic infarction with midbrain involvement, where the correct diagnosis was made retrospectively using computed tomography (CT) scan, magnetic resonance imaging (MRI), diffusionweighted imaging (DWI) and three-dimensional time-of-flight magnetic resonance angiography (3D TOF MRA).

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Pontine cavernoma haemorrhage at 24 weeks of pregnancy that resulted in eight-and-a-half syndrome

Cited by 13 publications

References 4 publications

Body Fluid Biomarkers for Alzheimer’s Disease—An Up-To-Date Overview

Body Fluid Biomarkers for Alzheimer’s Disease—An Up-To-Date Overview

A Rare Successful Multidisciplinary Team Management of Pontine Hemorrhage in Third Trimester of Pregnancy: A Case Report

Atypical posterior circulation strokes: a case-based review of rare anatomical variations involved

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