Polyvinylpyrrolidone (PVP)-Assisted Solvothermal Synthesis of Mesoporous TiO₂Nanoparticles as an Active Material for Enzymatic Electrochemical Glucose Sensor

Abstract

This study reports on an enzymatic glucose sensor based on mesoporous TiO2 nanoparticles (MTNPs) synthesized by a simple solvothermal method. The unique structure of MTNPs with a fairly homogenous shape, porous, and high crystallinity is the consequence of the use of PVP yang during the synthesis process. PVP plays an important role in creating the uniform morphology and mesoporous structure of MTNPs-2. The success of glucose oxidase immobilization on the surface of MTNPs was proven by FTIR and UV–vis characterizations. The prepared GCE/MTNPs-2/GOx electrode successfully detects glucose molecules with good sensing performance with a sensitivity of 0.4098 μA mM−1 cm−2, a wide linear range of 0.1–1 mM, and a relatively low detection limit of 73 μM.

A Review on the Progress of Optoelectronic Devices Based on TiO2 Thin Films and Nanomaterials

“…The electrochemical sensor is a good application platform for detecting phosphopeptides in clinical settings. The preparation of enzyme-induced glucose sensors based on mesoporous titanium dioxide nanoparticles (MTNPs) was investigated by Amri et al [ 44 ]. The fourier transform infrared (FTIR) spectra showed corresponding characteristic peaks, indicating the successful immobilization of GO x on the surface of MTNPs-2.…”

A Sensitive Electrochemical Assay for T4 Polynucleotide Kinase Activity Based on Fe3O4@TiO2 And Gold Nanoparticles Hybrid Probe Modified Magnetic Electrode

“…[26][27][28][29][30][31][32] To improve sensitivity, various nanomaterials are introduced in electrochemical sensors due to the their excellent optical and electric properties, unique structures, and good biocompatibility, such as metal nanoparticles and nanoclusters, carbon nanomaterials, quantum dots (QDs), metal−organic frameworks (MOFs), MXenes, semiconductors nanomaterials, and their nanocomposites. [32][33][34][35][36][37][38][39][40][41][42][43][44] Although great achievements of these electrochemical approaches have been developed for the detection of T4 PNK activity and screening its inhibitors, it still remains a challenge to develop more simple, rapid, accurate and sensitive methods for T4 PNK activity assay.…”