Polyurethane/poly(vinyl alcohol) hydrogels: Preparation, characterization and drug delivery

Mȃndru, Mihaela; Bercea, Maria; Grădinaru, Luiza Madalina; Ciobanu, Constantin; Drobotă, Mioara; Vlad, Stelian; Albulescu, Radu

doi:10.1016/j.eurpolymj.2019.05.049

Cited by 59 publications

(33 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It can be used in the synthesis of organic-inorganic hybrid membrane for biodiesel production [2] and has been regarded as appropriate matrix in microbial fuel cell applications [3]. PVA has also been used in production of biomedical hydrogels with high ability to swell [4]. Moreover, diversity of industrial applications of PVA has been reported such as optical and humidity sensors, food packaging, surgical devices, manufacture of polarizing sheet, and production of thin film transistors [5,6].…”

Section: Introductionmentioning

confidence: 99%

Structural Properties and Catalytic Activity of Binary Poly (vinyl alcohol)/Al2O3 Nanocomposite Film for Synthesis of Thiazoles

2020

View full text Add to dashboard Cite

A solution casting technique was applied to prepare a binary poly (vinyl alcohol)/Al2O3 nanocomposite. The structural properties of nanocomposite were investigated using Fourier-transform infrared spectra, field emission scanning electron microscope, energy dispersive X-ray analyses, and X-ray diffraction. The hybrid PVA/Al2O3 film exhibited a conspicuous catalytic performance for synthesis of thiazole derivatives under mild reaction conditions. Moreover, the optimization of catalytic efficiency and reusability of this nanocomposite have been investigated.

show abstract

Section: Introductionmentioning

confidence: 99%

Structural Properties and Catalytic Activity of Binary Poly (vinyl alcohol)/Al2O3 Nanocomposite Film for Synthesis of Thiazoles

2020

View full text Add to dashboard Cite

show abstract

“…However, it is often difficult for hydrophilic hydrogels to load hydrophobic drugs. At present, amphoteric PU is an ideal candidate for the production of drug-loaded hydrogels [ 152 , 153 ]. Lucas et al used PEG and PCL-triol to synthesize PU-based hydrogels through a one-pot method.…”

Section: Biomaterials For Preparing Hydrogelsmentioning

confidence: 99%

Hydrogel Preparation Methods and Biomaterials for Wound Dressing

Liang

et al. 2021

Life

128

View full text Add to dashboard Cite

Wounds have become one of the causes of death worldwide. The metabolic disorder of the wound microenvironment can lead to a series of serious symptoms, especially chronic wounds that bring great pain to patients, and there is currently no effective and widely used wound dressing. Therefore, it is important to develop new multifunctional wound dressings. Hydrogel is an ideal dressing candidate because of its 3D structure, good permeability, excellent biocompatibility, and ability to provide a moist environment for wound repair, which overcomes the shortcomings of traditional dressings. This article first briefly introduces the skin wound healing process, then the preparation methods of hydrogel dressings and the characteristics of hydrogel wound dressings made of natural biomaterials and synthetic materials are introduced. Finally, the development prospects and challenges of hydrogel wound dressings are discussed.

show abstract

“…It is noted that minicolumns in flow systems, which are filled with loaded PU foam, did not depict any overpressure or swelling, although this often occurs with the utilization of other sorbents [101]. Madru et al [102] had the contention that the water swelling of PU membranes was related to both its aggregation condition, as well as the temperature [102].…”

Section: Thermal Properties Of Nanofiller-tpu Nanocompositesmentioning

confidence: 99%

Investigating Physio-Thermo-Mechanical Properties of Polyurethane and Thermoplastics Nanocomposite in Various Applications

et al. 2021

View full text Add to dashboard Cite

The effect of the soft and hard polyurethane (PU) segments caused by the hydrogen link in phase-separation kinetics was studied to investigate the morphological annealing of PU and thermoplastic polyurethane (TPU). The significance of the segmented PUs is to achieve enough stability for further applications in biomedical and environmental fields. In addition, other research focuses on widening the plastic features and adjusting the PU–polyimide ratio to create elastomer of the poly(urethane-imide). Regarding TPU- and PU-nanocomposite, numerous studies investigated the incorporation of inorganic nanofillers such as carbon or clay to incorporating TPU-nanocomposite in several applications. Additionally, the complete exfoliation was observed up to 5% and 3% of TPU–clay modified with 12 amino lauric acid and benzidine, respectively. PU-nanocomposite of 5 wt.% Cloisite®30B showed an increase in modulus and tensile strength by 110% and 160%, respectively. However, the nanocomposite PU-0.5 wt.% Carbone Nanotubes (CNTs) show an increase in the tensile modulus by 30% to 90% for blown and flat films, respectively. Coating PU influences stress-strain behavior because of the interaction between the soft segment and physical crosslinkers. The thermophysical properties of the TPU matrix have shown two glass transition temperatures (Tg’s) corresponding to the soft and the hard segment. Adding a small amount of tethered clay shifts Tg for both segments by 44 °C and 13 °C, respectively, while adding clay from 1 to 5 wt.% results in increasing the thermal stability of TPU composite from 12 to 34 °C, respectively. The differential scanning calorimetry (DSC) was used to investigate the phase structure of PU dispersion, showing an increase in thermal stability, solubility, and flexibility. Regarding the electrical properties, the maximum piezoresistivity (10 S/m) of 7.4 wt.% MWCNT was enhanced by 92.92%. The chemical structure of the PU–CNT composite has shown a degree of agglomeration under disruption of the sp2 carbon structure. However, with extended graphene loading to 5.7 wt.%, piezoresistivity could hit 10-1 S/m, less than 100 times that of PU. In addition to electrical properties, the acoustic behavior of MWCNT (0.35 wt.%)/SiO2 (0.2 wt.%)/PU has shown sound absorption of 80 dB compared to the PU foam sample. Other nanofillers, such as SiO2, TiO2, ZnO, Al2O3, were studied showing an improvement in the thermal stability of the polymer and enhancing scratch and abrasion resistance.

show abstract

Polyurethane/poly(vinyl alcohol) hydrogels: Preparation, characterization and drug delivery

Cited by 59 publications

References 51 publications

Structural Properties and Catalytic Activity of Binary Poly (vinyl alcohol)/Al2O3 Nanocomposite Film for Synthesis of Thiazoles

Structural Properties and Catalytic Activity of Binary Poly (vinyl alcohol)/Al2O3 Nanocomposite Film for Synthesis of Thiazoles

Hydrogel Preparation Methods and Biomaterials for Wound Dressing

Investigating Physio-Thermo-Mechanical Properties of Polyurethane and Thermoplastics Nanocomposite in Various Applications

Contact Info

Product

Resources

About