“…These hazards are promoted by the early and quick adsorption of proteins abundant in a body fluid [31][32][33][34][35][36][37]. Since it is difficult to prepare an artificial material that rejects the adsorption of any kind of protein, it seems rather feasible to design a surface to selectively reject a kind of protein that would be the foundation for the following biological reactions.…”
“…These hazards are promoted by the early and quick adsorption of proteins abundant in a body fluid [31][32][33][34][35][36][37]. Since it is difficult to prepare an artificial material that rejects the adsorption of any kind of protein, it seems rather feasible to design a surface to selectively reject a kind of protein that would be the foundation for the following biological reactions.…”
“…Certain polyetherurethaneureas and a block copoly(dialkyl siloxane) urethane show a high albumin and a low fibrinogen adsorption [146,147]. This specific protein adsorption behavior of polyurethanes is not clear, although it may have to do with phase segregation in these polymers.…”
Section: Polymer Surface Modification and Blood Compatibilitymentioning
Published literature on biomedical polyurethanes is reviewed. Selected topics concerning chemistry, structure-property relations, tissue-material interactions, surface properties, applications, processing, and sterilization, etc., are discussed.
“…Polyether-based polyurethanes and avcothanes have been shown to possess good blood compatibility due to their high albumin and low fibrinogen adsorption [46]. Albumin-coated surfaces do not attract platelets and are supposed to prevent thrombosis better than bare surfaces.…”
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