Polyurethane Based Materials with Applications in Medical Devices

Davis, Fred J.; Mitchell, Geoffrey R.

doi:10.1007/978-0-387-47683-4_3

Cited by 41 publications

(34 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, PUs may be easily cross-linked, blended with other synthetic and/or natural-based polymers, and processed in the form of particles, fibers, films, foams and hydrogels [239]. PU-based nanofibers showed controlled evaporative water loss and promoted wound fluid drainage, which are essential characteristics for wound dressing materials [240,241]. When compared to other conventional dressings, some PU-based foam dressings showed higher healing capacities [237,238,241,242].…”

Section: Polyurethanes (Pus)mentioning

confidence: 99%

“…PU-based nanofibers showed controlled evaporative water loss and promoted wound fluid drainage, which are essential characteristics for wound dressing materials [240,241]. When compared to other conventional dressings, some PU-based foam dressings showed higher healing capacities [237,238,241,242]. A dressing constituted of polymeric fibers with repeated units containing urethane groups (aliphatic polyurethane, aromatic polyurethane, aliphatic polyurethane, aromatic polyurethane or a combination of them) was recently patented and presented as effective for the treatment of chronic wounds such as DFUs [237].…”

Section: Polyurethanes (Pus)mentioning

confidence: 99%

See 1 more Smart Citation

Recent advances on the development of wound dressings for diabetic foot ulcer treatment—A review

et al. 2013

View full text Add to dashboard Cite

a b s t r a c tDiabetic foot ulcers (DFUs) are a chronic, non-healing complication of diabetes that lead to high hospital costs and, in extreme cases, to amputation. Diabetic neuropathy, peripheral vascular disease, abnormal cellular and cytokine/chemokine activity are among the main factors that hinder diabetic wound repair. DFUs represent a current and important challenge in the development of novel and efficient wound dressings. In general, an ideal wound dressing should provide a moist wound environment, offer protection from secondary infections, remove wound exudate and promote tissue regeneration. However, no existing dressing fulfills all the requirements associated with DFU treatment and the choice of the correct dressing depends on the wound type and stage, injury extension, patient condition and the tissues involved. Currently, there are different types of commercially available wound dressings that can be used for DFU treatment which differ on their application modes, materials, shape and on the methods employed for production. Dressing materials can include natural, modified and synthetic polymers, as well as their mixtures or combinations, processed in the form of films, foams, hydrocolloids and hydrogels. Moreover, wound dressings may be employed as medicated systems, through the delivery of healing enhancers and therapeutic substances (drugs, growth factors, peptides, stem cells and/or other bioactive substances). This work reviews the state of the art and the most recent advances in the development of wound dressings for DFU treatment. Special emphasis is given to systems employing new polymeric biomaterials, and to the latest and innovative therapeutic strategies and delivery approaches.

show abstract

Section: Polyurethanes (Pus)mentioning

confidence: 99%

Section: Polyurethanes (Pus)mentioning

confidence: 99%

Recent advances on the development of wound dressings for diabetic foot ulcer treatment—A review

et al. 2013

View full text Add to dashboard Cite

show abstract

“…For this reason, they are usually made separately and joined together via adhesives or by welding [14,15]. Thermoplastic Polyurethane Elastomers (TPUs) are widely used for catheters and dynamic stents [15][16][17][18][19]. The elastomeric nature derives from its blocky structure whose polymeric chains are composed of alternating sequences of low glass transition (soft) segments and more rigid (hard) segments that soften at higher temperatures.…”

Section: Introductionmentioning

confidence: 99%

Polyurethane-Based Composites: Effects of Antibacterial Fillers on the Physical-Mechanical Behavior of Thermoplastic Polyurethanes

et al. 2020

View full text Add to dashboard Cite

The challenge to manufacture medical devices with specific antibacterial functions, and the growing demand for systems able to limit bacterial resistance growth, necessitates the development of new technologies which can be easily produced at an industrial level. The object of this work was the study and the development of silver, titanium dioxide, and chitosan composites for the realization and/or implementation of biomedical devices. Thermoplastic elastomeric polyurethane was selected and used as matrix for the various antibacterial functions introduced during the processing phase (melt compounding). This strategy was employed to directly incorporate antimicrobial agents into the main constituent material of the devices themselves. With the exception of the composite filled with titanium dioxide, all of the other tested composites were shown to possess satisfactory mechanical properties. The best antibacterial effects were obtained with all the composites against Staphylococcus aureus: viability was efficiently inhibited by the prepared materials in four different bacterial culture concentrations.

show abstract

“…The products made of this material can be sterilized by plasma [14]. In medicine, the biocompatible versions of the TPU material are used in conventional manufacturing of prostheses, implants, support structures for tissue regeneration and artificial blood vessels [9]. The mechanical properties of TPU, such as viscosity and hardness, can be applied in the layered additive manufacturing process of FDM.…”

Section: Introductionmentioning

confidence: 99%

Prototyping of an Individualized Multi-Material Wrist Orthosis using Fused Deposition Modelling

Górski¹,

Kuczko²,

Weiss³

et al. 2019

Adv. Sci. Technol. Res. J.

View full text Add to dashboard Cite

The paper presents the design and manufacturing process of an individualized wrist orthosis. The patient's upper limb was 3D scanned and the orthosis was designed using a CAD system. Each part of the orthosis consists of two different materials that fulfill different functions. By using the double-head Fused Deposition Modelling machine it was possible to produce these parts in a single process without the need for additional assembly operations. The orthosis has been tested for mutual fit of parts, strength and comfort of use.

show abstract

Polyurethane Based Materials with Applications in Medical Devices

Cited by 41 publications

References 51 publications

Recent advances on the development of wound dressings for diabetic foot ulcer treatment—A review

Recent advances on the development of wound dressings for diabetic foot ulcer treatment—A review

Polyurethane-Based Composites: Effects of Antibacterial Fillers on the Physical-Mechanical Behavior of Thermoplastic Polyurethanes

Prototyping of an Individualized Multi-Material Wrist Orthosis using Fused Deposition Modelling

Contact Info

Product

Resources

About